Comparative activity in vitro of 16 antimicrobial agents against penicillin-susceptible meningococci and meningococci with diminished susceptibility to penicillin.

Antimicrobial Agents and Chemotherapy
E Pérez TralleroI Muñoz Baroja

Abstract

Broad-spectrum cephalosporins were very active against strains of Neisseria meningitidis with both penicillin susceptibility and diminished penicillin susceptibility. Ceftriaxone was the most active antibiotic. Increases in MIC for 90% of meningococci with diminished susceptibility to penicillin of greater than or equal to 16-fold were observed for amdinocillin, cefuroxime, aztreonam, and imipenem; 2-fold increases were observed for ceftazidime, mezlocillin, and piperacillin. No differences were observed for non-beta-lactam antibiotics.

References

Jan 1, 1989·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·D FontanalsJ C Rojo
Mar 19, 1988·Lancet·E M SutcliffeA Percival
Oct 1, 1987·Epidemiology and Infection·J A Sáez-NietoJ L Perez-Saenz
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Citations

Sep 1, 1993·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·A BäckmannP Olcén
May 5, 1990·Lancet·E Pérez-TralleroE G Pérez-Yarza
Sep 5, 2001·The Journal of Infection·R A Wall
Dec 27, 2013·The Journal of Veterinary Medical Science·Hiroya ItoHirofumi Yuzawa
Mar 25, 1998·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·E Perez-TralleroJ M Marimon
Jun 1, 2000·Infectious Disease Clinics of North America·M H Chowdhury, A R Tunkel
Apr 4, 1991·The New England Journal of Medicine·G RileyC Krishnan
Sep 1, 1994·Journal of Clinical Microbiology·E Pérez-TralleroJ M García-Arenzana

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D FontanalsJ C Rojo
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