Comparative analysis of magnetic resonance imaging and pathological findings of microcystic meningioma and meningeal Ewing sarcoma/peripheral primitive neuroectodermal tumors.

Acta neurologica Belgica
Jing ZhangJunlin Zhou

Abstract

Microcystic meningiomas (MCMs) and meningeal Ewing sarcoma/peripheral primitive neuroectodermal tumours (pPNETs) are difficult to differentiate because of the similarity in their image manifestation on magnetic resonance imaging (MRI). Differential diagnosis of these two tumours before surgery could contribute to ameliorating clinical decision-making, and predicting prognosis. Here, we aimed to comparatively analyse the difference between MRI and pathological findings of these two tumours. Thirteen cases of MCM and eleven cases of meningeal Ewing sarcoma/pPNET confirmed through pathology were analysed retrospectively. The imaging features of the two tumours were statistically analysed using the Chi square test. The average age of patients with MCM and meningeal Ewing sarcoma/pPNET was 47 ± 18.4 years and 20 ± 13.2 years, respectively. Features of MRI, including tumour morphology, dural tail sign, bony destruction, and distant metastasis, were significantly different between the two tumours (p < 0.001). T1-weighted (T1W) signal and enhanced features resulted in a p value of < 0.05. There were no significant differences in the T2-weighted (T2W) signal and peri-tumoural oedema (p > 0.05). MCM immunohistochemistry showed that all t...Continue Reading

References

Oct 1, 1973·Cancer·M N Hart, K M Earle
Jul 1, 1993·Brain Pathology·P KleihuesB W Scheithauer
Feb 1, 1996·European Journal of Radiology·C IbarburenE A Zerhouni
Jun 9, 2005·Hematology/oncology Clinics of North America·Richard Carvajal, Paul Meyers
Oct 1, 2013·European Journal of Radiology·Xu QianLi Jingjing
Sep 7, 2016·The Lancet Oncology·Roland GoldbrunnerMichael Weller
Feb 16, 2017·Acta neurologica Belgica·Mehmet Cagri DanismanYahya Paksoy
Aug 2, 2019·Anticancer Research·Raamis KhwajaEdward Pan

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