Comparative analysis of plant MKK gene family reveals novel expansion mechanism of the members and sheds new light on functional conservation

BMC Genomics
Min Jiang, Zhaoqing Chu

Abstract

Mitogen-activated protein kinase (MAPK) cascades play critical functions in almost every aspect of plant growth and development, which regulates many physiological and biochemical processes. As a middle nodal point of the MAPK cascades, although evolutionary analysis of MKK from individual plant families had some reports, their evolutionary history in entire plants is still not clear. To better understand the evolution and function of plant MKKs, we performed systematical molecular evolutionary analysis of the MAPKK gene family and also surveyed their gene organizations, sequence features and expression patterns in different subfamilies. Phylogenetic analysis showed that plant MAPKK fall into five different groups (Group A-E). Majority orthology groups seemed to be a single or low-copy genes in all plant species analyzed in Group B, C and D, whereas group A MKKs undergo several duplication events, generating multiple gene copies. Further analysis showed that these duplication events were on account of whole genome duplications (WGDs) in plants and the duplicate genes maybe have undergone functional divergence. We also found that group E MKKs had mutation with one change of serine or theronine might lead to inactivity originated...Continue Reading

References

Sep 1, 1997·Nucleic Acids Research·S F AltschulD J Lipman
Dec 30, 1998·Trends in Biochemical Sciences·A J Whitmarsh, R J Davis
Dec 4, 2001·Biology of the Cell·H Enslen, R J Davis
Mar 5, 2002·Nature·Tsuneaki AsaiJen Sheen
May 22, 2002·International Review of Cytology·Susanne M Steggerda, Bryce M Paschal
Jun 5, 2002·The Plant Cell·Liming XiongJian-Kang Zhu
Jul 18, 2002·Trends in Plant Science·UNKNOWN MAPK Group
Mar 18, 2003·Cellular Signalling·Takuji Tanoue, Eisuke Nishida
Sep 4, 2003·Genome Research·Li LiDavid S Roos
Oct 12, 2004·FEBS Letters·Balázs MelikantCathal Wilson
Apr 1, 2005·Proceedings of the National Academy of Sciences of the United States of America·Steven MaereYves Van de Peer
Dec 22, 2005·The Plant Journal : for Cell and Molecular Biology·Brody J DeYoungSteven E Clark
Mar 16, 2006·Trends in Plant Science·Louis-Philippe HamelBrian E Ellis
Jun 6, 2006·Proteins·Chin-Sheng YuJenn-Kang Hwang
Aug 4, 2006·Methods : a Companion to Methods in Enzymology·Lee Bardwell, Kandarp Shah
Dec 6, 2006·Nucleic Acids Research·Shu OuyangC Robin Buell
Feb 6, 2008·The Plant Journal : for Cell and Molecular Biology·Yu XingJianhua Zhang
Apr 26, 2008·Science·Haibao TangAndrew H Paterson
Dec 17, 2008·Proceedings of the National Academy of Sciences of the United States of America·Hongyun TongZheng-Hui He
Aug 5, 2009·Nature Reviews. Genetics·Yves Van de PeerAxel Meyer
Apr 17, 2010·DNA Research : an International Journal for Rapid Publication of Reports on Genes and Genomes·Kudupudi Prabhakara RaoAlok Krishna Sinha
May 6, 2010·Annual Review of Plant Biology·Maria Cristina Suarez RodriguezJohn Mundy
Apr 12, 2011·Nature·Yuannian JiaoClaude W dePamphilis
Nov 24, 2011·Nucleic Acids Research·David M GoodsteinDaniel S Rokhsar
Dec 6, 2011·Nucleic Acids Research·Philippe LameschEva Huala
Jan 28, 2012·Genome Biology·Yuannian JiaoClaude W Depamphilis
Nov 29, 2012·The Journal of Biological Chemistry·Marina A González Besteiro, Roman Ulm

❮ Previous
Next ❯

Citations

Jan 30, 2020·TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·Shantel A MartinezCamille M Steber
Nov 20, 2020·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·Jinrong BaiXianli Meng
Apr 24, 2021·PloS One·José Manuel González-CoronelÁngel Arturo Guevara-García

❮ Previous
Next ❯

Software Mentioned

InterProScan
GSDS
Gene Structure Display Server ( GSDS )
WebLogo
Molecular Evolution Genetic Analysis
DNASP
PhyloT
iTOL
MEGA
OrthoMCL

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.