Comparative analysis of proteinase, phospholipase, hydrophobicity and biofilm forming ability in Candida species isolated from clinical specimens

Journal de mycologie médicale
S DabiriM Razzaghi-Abyaneh

Abstract

Candida species are the commensal organisms of human and animal mucosa that cause a wide range of debilitating diseases in immunocompromised patients and other susceptible individuals. The present study aimed to investigate the ability of clinical isolates of various Candida species to produce proteinase and phospholipase, hydrophobicity and biofilm forming ability that assumed to have a vital role in Candida pathogenicity. Eighty-four Candida strains belonged to Candida albicans (44.1%), C. glabrata (5.9%), C. guilliermondii (5.9%), C. krusei (10.8%), C. parapsilosis (26.2%), and C. tropicalis (7.1%) were examined for proteinase and phospholipase production, cell surface hydrophobicity and biofilm forming ability. The production of proteinase and phospholipase was detected in 81 (96.4%) and 79 (94.1%) of the strains, respectively. C. albicans showed the highest proteinase and phospholipase activity (mean Pz values of 0.42±0.25 and 0.72±0.28) and biofilm formation ability (0.66±0.22). C. parapsilosis had the highest hydrophobicity (42.97±16.1), which showed a good correlation with biofilm formation ability. A considerable percentage of non-albicans Candida strains produced significant amounts of proteinase and phospholipase wit...Continue Reading

Citations

Jul 18, 2020·International Journal of Microbiology·Hasti NouraeiKeyvan Pakshir
Mar 16, 2019·Medical Mycology·Laura Judith Marcos-ZambranoJesús Guinea
Oct 28, 2019·Critical Reviews in Food Science and Nutrition·Rosanna TofaloCharles M A P Franz
Aug 11, 2020·International Microbiology : the Official Journal of the Spanish Society for Microbiology·Wafa RhimiClaudia Cafarchia
Aug 27, 2019·Journal de mycologie médicale·C SriphannamA Kummasook
Sep 25, 2020·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Arumugam GaneshkumarRajendran Rajaram
Dec 3, 2020·Frontiers in Microbiology·Carmen Rodríguez-CerdeiraJosé Luís González-Cespón
Feb 12, 2021·Frontiers in Cellular and Infection Microbiology·Carina Danchik, Arturo Casadevall
May 15, 2021·Journal of Clinical Laboratory Analysis·Hadis JafarianAli Zarei Mahmoudabadi

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