Comparative analysis of quality-of-life metrics after endoscopic surgery for sinonasal neoplasms

American Journal of Rhinology & Allergy
Nathan A DeckardPete S Batra

Abstract

The objective of this study was to evaluate the postoperative quality of life (QOL) after endoscopic resection of sinus and skull base neoplasms using validated outcomes measures and to perform correlation of the various metrics to better discern their efficacy. Prospective QOL data collection and retrospective chart review were performed. QOL data were collected using the 20-item Sino-Nasal Outcome Test (SNOT-20), Anterior Skull Base Questionnaire (ASBQ), European Quality-of-Life-5 Dimension (EQ-5D) questionnaire, and Lund-Kennedy endoscopic (LKE) score in 71 patients with sinonasal and skull base tumors. The mean age was 53 years and mean follow-up was 14.5 months at the time QOL data were collected. Benign and malignant tumors represented 39 (54.9%) and 32 (45.1%) cases, respectively. Twenty malignancies (62.5%) were stage T3 or T4, and 23 required postoperative chemotherapy and radiation (CRT). Factors indicating worsened postoperative QOL included malignant histopathology, T3 or T4 tumors, and the use of postoperative CRT (p < 0.05). There was a strong correlation of ASBQ with EQ-5D and SNOT-20 scores (r < -0.5) and a moderate correlation between the SNOT-20 and EQ-5D (r > 0.3), and the LKE had moderate correlation with SN...Continue Reading

References

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May 1, 2013·American Journal of Rhinology & Allergy·Patrick T Hennessey, Douglas D Reh
May 1, 2013·American Journal of Rhinology & Allergy·Richard J Harvey, Dustin M Dalgorf

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Citations

Feb 17, 2017·American Journal of Rhinology & Allergy·Kazuhiro OmuraYasuhiro Tanaka
Dec 21, 2018·International Forum of Allergy & Rhinology·Brandon K NguyenJean Anderson Eloy
Nov 5, 2020·American Journal of Rhinology & Allergy·Gabriele MolteniDaniele Marchioni

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