Comparative analysis of the 2016 ACR-EULAR and the 2002 AECG classification criteria for Sjögren's syndrome: Findings from the NIH cohort

Oral Diseases
M BillingsI Alevizos

Abstract

The introduction of new classification criteria for Sjögren's syndrome, known as the 2016 American College of Rheumatology/European League against Rheumatism Classification Criteria (ACR-EULAR), created a need for the evaluation of its performance in an external cohort. The purpose of this study was to compare the performance of the 2016 ACR-EULAR classification set with the widely used American-European Consensus Group Classification criteria (AECG) in the cohort at the National Institutes of Health, USA, and to compare the performance of the sets in classifying both primary and secondary Sjögren's syndrome (pSS and sSS). The study cohort at the NIH (N = 1,303) was enrolled for clinical suspicion of SS. Participants were classified as SS, pSS, and sSS according to both classification sets. Performance of 2016 ACR-EULAR and AECG sets was compared holding each as gold standard to the other. Statistical analysis of test diagnostics and agreement between the two sets were undertaken. By the AECG set, 701 were classified as having SS (627 pSS, 74 sSS) and 714 were classified with SS (647 pSS, 67 sSS) by the 2016 ACR-EULAR set. Sensitivity and specificity of the two sets were comparable in classifying SS, pSS, and sSS. There was hig...Continue Reading

References

Jun 11, 1975·Oral Surgery, Oral Medicine, and Oral Pathology·T E DanielsN Talal
May 1, 1986·Arthritis and Rheumatism·R I FoxF V Howell
May 15, 2002·Annals of the Rheumatic Diseases·C VitaliUNKNOWN European Study Group on Classification Criteria for Sjögren's Syndrome
May 9, 2012·Arthritis Care & Research·S C ShiboskiUNKNOWN Sjögren's International Collaborative Clinical Alliance (SICCA) Research Groups
May 20, 2017·Annals of the Rheumatic Diseases·Claudio Vitali, Nicoletta Del Papa

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Citations

May 29, 2018·Clinical Rheumatology·Xiaoyun ChenWei Wei
Jun 7, 2020·Clinical Rheumatology·Veli YazisizMustafa Ender Terzioğlu
Nov 16, 2020·Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology·Simon Kold BredahlAnne Marie Lynge Pedersen
Nov 25, 2020·Journal of Korean Medical Science·Hyoungyoung KimYoon Kyoung Sung
May 17, 2021·Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology·Alaa F BukhariAruna Ramesh

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