Comparative analysis of total body and dermatoscopic photographic monitoring of nevi in similar patient populations at risk for cutaneous melanoma.

Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]
Agnessa Gadeliya GoodsonDouglas Grossman

Abstract

Our previous experience monitoring nevi in high-risk patients using serial digital epiluminescence microscopy (DELM) photography achieved low biopsy rates but was limited by melanomas presenting as new lesions or arising from nevi that had not been photographed. To determine whether biopsy rates, efficiency of melanoma detection, and melanoma origin (de novo vs nevus derived) differed in a similar patient population monitored using total body (TB) photography. One thousand seventy-six patients (including 187 from a prior cohort) underwent TB photography and were monitored using photographs obtained at the initial visit. Risk factors and median monitoring periods for these patients were comparable with those of patients previously monitored using DELM photography. Two hundred seventy-five biopsies were performed in 467 patients on follow-up visits. Of 12 melanomas detected on follow-up, five were invasive, five presented as changing lesions and two as new lesions, nine arose de novo, and the remainder were nevus derived. In our experience with both approaches, monitoring patients at risk for melanoma using TB photography was associated with lower biopsy rates and lower nevus-to-melanoma ratios than using DELM and facilitated det...Continue Reading

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Citations

Mar 18, 2011·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Vincenzo De GiorgiTorello Lotti
Jul 28, 2011·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Agnessa Gadeliya GoodsonDouglas Grossman
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Apr 17, 2021·The Australasian Journal of Dermatology·Jennifer NguyenVictoria Mar

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