PMID: 7083820Jan 1, 1982Paper

Comparative and developmental studies on 4-hydroxy-2-oxoglutarate aldolase and hydroxyproline oxidase

Comparative Biochemistry and Physiology. B, Comparative Biochemistry
J A CarnieK V Rowsell


1. In rats, liver 4-hydroxy-2-oxoglutarate aldolase and hydroxyproline oxidase activities are maximal in the suckling period. 2. Liver activities for 4-hydroxy-2-oxoglutarate aldolase, alanine-glyoxylate aminotransferase, serine-pyruvate aminotransferase and serine dehydratase, but not hydroxyproline oxidase, are increased in rats on a high-fat, carbohydrate-free diet. 3. It is suggested that 4-hydroxy-2-oxoglutarate may be a significant source of glyoxylate for glycine and hence glucose formation. 4. Mammalian liver hydroxyproline oxidase activity is higher in carnivorous species; necessary, perhaps, to metabolise a relatively large influx of hydroxyproline on a flesh diet.


Jan 1, 1979·Comparative Biochemistry and Physiology. B, Comparative Biochemistry·E V RowsellK V Rowsell
Jul 8, 1969·Biochimica Et Biophysica Acta·H Nishihara, E E Dekker
Nov 11, 1966·Biochemical and Biophysical Research Communications·R D Kobes, E E Dekker
Jan 11, 1967·Biochimica Et Biophysica Acta·L D AronsonE ADAMS
Jan 1, 1958·Biochimica Et Biophysica Acta·N B MADSEN
Dec 1, 1958·Journal of Cellular Physiology·H B BurchS R LOWRY
Jun 4, 1963·Biochimica Et Biophysica Acta·F J BALLARD, I T Oliver

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