Comparative aspects of methemoglobin formation and reduction in opossum (Didelphis virginiana) and human erythrocytes

Comparative Biochemistry and Physiology. A, Comparative Physiology
N C BethlenfalvayT L Waldrup


Glucose-depleted, nitrite-treated opossum erythrocytes effectively reduce methemoglobin in an environment of physiological saline and added glucose does not accelerate the rate of reduction. In autologous plasma or 25 mM phosphate-buffered saline pH 7.4, added glucose significantly accelerates methemoglobin reduction in glucose-depleted, nitrite-treated opossum erythrocytes. Human red cells require added glucose to carry out reduction of methemoglobin and increased phosphate concentration or autologous plasma does not alter the rate of this process. Within the opossum red cell in vitro, autooxidation of hemoglobin proceeds at a much slower rate than that observed in human erythrocytes.


Apr 15, 1978·FEBS Letters·A TomodaY Yoneyama
Mar 1, 1969·The American Journal of Physiology·A OmachiT E Parry
Aug 1, 1971·The Journal of Clinical Investigation·S A FeigD G Nathan
Jun 26, 1972·Biochimica Et Biophysica Acta·J M Rifkind
Sep 26, 1966·Biochimica Et Biophysica Acta·J NivE Dimant
Jan 1, 1982·Comparative Biochemistry and Physiology. B, Comparative Biochemistry·M E JohnM R Waterman
Jan 1, 1982·Comparative Biochemistry and Physiology. B, Comparative Biochemistry·N C BethlenfalvayT L Waldrup
Jun 1, 1962·The Journal of Clinical Investigation·R G CHAPMANB W GABRIO
Dec 1, 1964·The Journal of Pediatrics·P BALSAMOE M SCOTT
Sep 1, 1959·The Journal of Clinical Investigation·E R JAFFE


Jan 1, 1986·Comparative Biochemistry and Physiology. B, Comparative Biochemistry·E Reischl
Mar 1, 1997·Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology·A L Dafré, E Reischl
Jan 1, 1990·Food Additives and Contaminants·P BatinaM T Mitjavila
May 1, 1988·Biological Reviews of the Cambridge Philosophical Society·A van Waarde

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