Comparative effect of a new mouthrinse containing chlorhexidine, triclosan and zinc on volatile sulphur compounds: a randomized, crossover, double-blind study

International Journal of Dental Hygiene
L MendesM G Pinto

Abstract

The aims of this study were to compare the volatile sulphur compounds (VSC)-reducing effect of two commercial mouthrinses using a morning bad breath model and to assess the role of mechanical plaque control (MPC) when performed previously to mouthrinse use. Eleven volunteers with good oral health were enrolled in a double-blind, randomized, six-step crossover design study with a 7-day washout period. Two commercial mouthrinses were tested using a saline solution (NaCl 0.9%) as a negative control: one mouthrinse contained 0.05% chlorhexidine, 0.05% cetylpyridinium chloride and 0.14% zinc lactate (CHX-CPC-Zn), while the other contained 0.05% chlorhexidine, 0.15% triclosan and 0.18% zinc pidolate (CHX-triclosan-Zn). A portable sulphide monitor (Halimeter(®) ) was used for VSC quantification. Measurements were made at baseline, and 1, 3 and 5 h after rinsing. Significant differences were detected by analysis of variance. No significant differences between groups were detected at baseline. We were unable to demonstrate a significant influence of mechanical plaque control on the reduction of VSC levels when performed before mouthrinse use (P = 0.631). Both mouthrinses effectively lowered VSC levels in all test intervals (P < 0.05). N...Continue Reading

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Citations

Jan 25, 2018·Journal of Applied Oral Science : Revista FOB·Nao SuzukiTakashi Hanioka
Mar 31, 2019·Molecular Oral Microbiology·Nao SuzukiTakashi Hanioka
Dec 12, 2019·The Cochrane Database of Systematic Reviews·Sumanth Kumbargere NagrajEby Varghese
Feb 18, 2017·Journal of Breath Research·Francisco Wilker Mustafa Gomes MunizCassiano Kuchenbecker Rösing
Jun 20, 2020·Brazilian Dental Journal·Stela Lima Farias de MirandaBruno Bueno-Silva

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