Comparative Effectiveness of Hybrid Ablation Versus Endocardial Catheter Ablation Alone in Patients With Persistent Atrial Fibrillation

JACC. Clinical Electrophysiology
David C KressJasbir Sra

Abstract

The outcomes of hybrid ablation versus endocardial catheter ablation alone were evaluated in patients with persistent and long-standing persistent atrial fibrillation (AF). Variable outcomes exist following endocardial catheter ablation in medically refractory patients with persistent AF. A hybrid epicardial-endocardial approach has emerged as an alternative to endocardial ablation. In 133 consecutive patients, 69 received endocardial ablation alone (pulmonary vein isolation and radiofrequency catheter ablation [endo group]) and 64 received endocardial catheter ablation and epicardial ablation (hybrid group). Recurrence was defined as any arrhythmia following the 3-month blanking period. Patients were followed for a median of 16 months. The hybrid and endo groups were similar in age (61 ± 10 years vs. 62 ± 8 years), body mass index (35 ± 6 kg/m2 vs. 35 ± 7 kg/m2), CHA2D2-VASc score (2 ± 1 vs. 2 ± 1), and ejection fraction (54 ± 11% vs. 53 ± 8%). The hybrid group had longer AF duration (median [interquartile range (IQR)] (12 months [IQR: 8 to 28 months] vs. 7 months [IQR: 5 to 12 months]; p < 0.001) and more previous ablations (58% vs. 25%; p < 0.001). Both groups had similar antiarrhythmic drug use at follow-up (55% vs. 48%). T...Continue Reading

References

Apr 30, 2002·American Journal of Epidemiology·Wendy A WattigneyJanet B Croft
Nov 3, 2004·Circulation·Pierre JaïsMichel Haïssaguerre
Nov 24, 2005·Journal of Cardiovascular Electrophysiology·Gaetano FassiniPaolo Della Bella
Jul 4, 2009·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Kurt C Roberts-ThomsonJonathan M Kalman
Jul 28, 2009·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·João AbecasisAniceto Silva
Nov 6, 2009·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Arash AryaChristopher Piorkowski
Mar 9, 2010·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Anthony G BrooksPrashanthan Sanders
May 22, 2010·Journal of Cardiovascular Electrophysiology·Ethan M BalkStanley Ip
Dec 15, 2010·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·James W McCreadyAnthony W Chow
Feb 23, 2011·Journal of Interventional Cardiac Electrophysiology : an International Journal of Arrhythmias and Pacing·Timo WeimarRalph J Damiano
Apr 5, 2011·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Jason G AndradeMarc Dubuc
Jun 30, 2012·Journal of the American College of Cardiology·Laurent PisonHarry J Crijns
Oct 16, 2012·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Anil K GehiAndy C Kiser
Mar 19, 2013·Journal of the American College of Cardiology·Douglas L PackerUNKNOWN STOP AF Cryoablation Investigators

❮ Previous
Next ❯

Citations

Sep 15, 2019·Journal of Interventional Cardiac Electrophysiology : an International Journal of Arrhythmias and Pacing·Carlo de AsmundisMark La Meir
Oct 13, 2020·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Kevin J MakatiJonathan S Steinberg
Mar 9, 2021·Journal of Interventional Cardiac Electrophysiology : an International Journal of Arrhythmias and Pacing·Giuseppe De MartinoGiuseppe Speziale
Jun 28, 2021·Journal of Cardiothoracic Surgery·Giuseppe NassoGiuseppe Speziale

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antiarrhythmic Agents: Mechanisms of Action

Understanding the mechanism of action of antiarrhythmic agents is essential in developing new medications as treatment of cardiac arrhythmias is currently limited by the reduced availability of safe and effective drugs. Discover the latest research on Antiarrhythmic Agents: Mechanism of Action here.

Anti-Arrhythmic Drug Therapies

Anti-arrhythmic drugs are used to prevent abnormal heart rhythms. These medications are used in conditions including, ventricular tachycardia, ventricular fibrillation and atrial fibrillation. Discover the latest research on anti-arrhythmic drug therapies here.

Arrhythmia

Arrhythmias are abnormalities in heart rhythms, which can be either too fast or too slow. They can result from abnormalities of the initiation of an impulse or impulse conduction or a combination of both. Here is the latest research on arrhythmias.

Atrial Fibrillation

Atrial fibrillation is a common arrhythmia that is associated with substantial morbidity and mortality, particularly due to stroke and thromboembolism. Here is the latest research.

Atrial Filbrillation

Atrial fibrillation refers to the abnormal heart rhythm characterized by rapid and irregular beating of the atria. Here is the latest research.

Related Papers

Heart Rhythm : the Official Journal of the Heart Rhythm Society
Mohamed BassiounyOussama M Wazni
Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology
Demosthenes KatritsisKenneth A Ellenbogen
© 2022 Meta ULC. All rights reserved