PMID: 9550454Apr 29, 1998Paper

Comparative effects of chromium, vanadium and gymnema sylvestre on sugar-induced blood pressure elevations in SHR

Journal of the American College of Nutrition
Harry G PreussR A Anderson

Abstract

Effects on systolic blood pressure (SBP) of ingesting three agents reported to influence insulin metabolism, i.e., chromium polynicotinate, bis(maltolato)oxovanadium (BMOV), and the herb, Gymnema sylvestre, were assessed simultaneously in spontaneously hypertensive rats (SHR). In the first study, SHR were fed either a starch, sugar, or sugar diet containing chromium polynicotinate, bis(maltolato)oxovanadium (BMOV), or G. sylvestre. Tail SBP was estimated indirectly and various blood chemistries were measured. TBARS formation was determined in hepatic and renal tissue. In a second study, tail SBP was measured in SHR ingesting diets containing different concentrations of BMOV. Compared to starch, SHR consuming sucrose showed a significant elevation of SBP within days that was maintained for the duration of study. Addition of chromium polynicotinate to the sucrose diet at the beginning of study prevented the sucrose-induced elevation of SBP for 2 weeks, but SBP rose significantly after that. BMOV at high concentrations overcame the sucrose-induced rise in SBP and even decreased SBP below values seen in SHR eating the starch diet, but marked weight loss was noted. A second study examined different concentrations of BMOV. At 0.01% w...Continue Reading

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Citations

Sep 27, 2002·Toxicology·Debasis BagchiHarry G Preuss
May 22, 2002·Journal of Ethnopharmacology·J K GroverV Vats
Jul 11, 2001·Journal of the American College of Nutrition·R A AndersonA Kerkeni
Oct 29, 2008·Evidence-based Complementary and Alternative Medicine : ECAM·Abdelaziz S Abu El-Saad, Hamada M Mahmoud
Apr 10, 2008·Journal of Clinical Biochemistry and Nutrition·Manisha ModakThomas Paul A Devasagayam
Feb 11, 2014·BMC Complementary and Alternative Medicine·Abdulaziz M AleisaMohammed M Ahmed
Apr 20, 2014·Journal of Cancer Research and Clinical Oncology·Mousa O Germoush, Ayman M Mahmoud
Jun 1, 2014·Archivum Immunologiae Et Therapiae Experimentalis·Mahmoud Abdel-LatifAl-Mahy El-Mallah
Apr 23, 2013·American Journal of Physiology. Heart and Circulatory Physiology·John D BosseThunder Jalili
Dec 7, 2013·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Giovanni Di FabioArmando Zarrelli
Jul 3, 2015·Experimental and Therapeutic Medicine·Amal Jamil FataniMohammed Mahboobuddin Ahmed
Jun 6, 2012·International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience·O M AhmedS M Abd El-Tawab
Oct 14, 2011·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·Laila A RashedHala M Soliman
Mar 9, 2011·Experimental and Toxicologic Pathology : Official Journal of the Gesellschaft Für Toxikologische Pathologie·Ayman Moawad Mahmoud
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Mar 24, 2009·Life Sciences·Wen-Ying ChenFrank Chiahung Mao
Jan 18, 2011·The Journal of Pharmacy and Pharmacology·Subhrojit SenAbhay Sankar Chakraborti
Apr 28, 2016·Evidence-based Complementary and Alternative Medicine : ECAM·Abeer HanafySeham El-Sayed Abdel-Hady
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Apr 19, 2015·Behavioral and Brain Functions : BBF·Jamaan AjaremMohammad I Sabri
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Mar 9, 2017·BMC Complementary and Alternative Medicine·Abdul MalikAnwarul-Hassan Gilani
May 2, 2017·Journal of Medicinal Food·Laura Y ZuñigaEsperanza Martínez-Abundis

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