Comparative effects of different whole grains and brans on blood lipid: a network meta-analysis

European Journal of Nutrition
Suocheng HuiMantian Mi

Abstract

The comparative effects of different whole grains and brans on blood lipid are still not totally elucidated. We aimed to estimate and rank the effects of different whole grains and brans on the control of blood lipid. We performed a strategic literature search of PubMed, EMBASE and the Cochrane Library for relevant trials. Both pairwise meta-analyses and network meta-analyses were conducted to compare and rank the intervention strategies of whole grains and brans for the control of total cholesterol (TC), LDL cholesterol (LDL-C), HDL cholesterol (HDL-C), and triglycerides (TG). Fifty-five eligible trials with a total of 3900 participants were included. Cumulative ranking analyses showed that oat bran was the most effective intervention strategy for TC and LDL-C improvements, with significant decreases of - 0.35 mmol/L (95% CI - 0.47, - 0.23 mmol/L) and - 0.32 mmol/L (95% CI - 0.44, - 0.19 mmol/L) in TC and LDL-C compared with control, respectively. In comparison with control, oat was associated with significant reductions in TC by - 0.26 mmol/L (95% CI - 0.36, - 0.15 mmol/L) and LDL-C by - 0.17 mmol/L (95% CI - 0.28, - 0.07 mmol/L), which was ranked as the second best treatment. Barley, brown rice, wheat and wheat bran were sho...Continue Reading

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Citations

Nov 2, 2018·European Journal of Nutrition·Lukas SchwingshacklAnna Chaimani
Aug 3, 2019·The American Journal of Clinical Nutrition·Mohammad Ishraq ZafarLu-Lu Chen
Dec 13, 2019·Stroke; a Journal of Cerebral Circulation·Line LyskjærChristina C Dahm
May 4, 2021·Critical Reviews in Food Science and Nutrition·Wen ChengHaifeng Qian
Nov 7, 2021·Nutrition Reviews·Kaisa S PoutanenRikard Landberg

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Software Mentioned

R
Cochrane
meta package
Stata

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