Comparative efficacy of a 12 week yoga-based lifestyle intervention and dietary intervention on adipokines, inflammation, and oxidative stress in adults with metabolic syndrome: a randomized controlled trial

Translational Behavioral Medicine
Rashmi YadavRavindra Mohan Pandey

Abstract

The present randomized controlled trial (RCT) evaluated the comparative efficacy of 12 week yoga-based lifestyle intervention (YBLI) and dietary intervention (DI) alone on adipokines, inflammation, and oxidative stress in Indian adults with metabolic syndrome (Met S). A parallel, two arm, RCT was conducted in Integral Health Clinic (IHC), All India Institute of Medical Sciences, India from 2012 to 2014. IHC is an outpatient facility conducting YBLI programs for prevention and management of chronic diseases. Two hundred sixty men and women (20-45 years) visiting the outpatient department of a tertiary care hospital were diagnosed with Met S and randomized 1:1 to receive 12 week YBLI (n = 130) or DI (n = 130). Primary outcomes were change in plasma levels of adipokines (leptin, adiponectin, and leptin:adiponectin ratio), markers of inflammation (tumor necrosis factor [TNF]-α, interleukin [IL]-6), markers of oxidative stress (thiobarbituric acid reactive substances [TBARS], 8-hydroxy-2'-deoxyguanosine [8-OHdG], and superoxide dismutase [SOD]) measured at baseline, 2 weeks, and 12 weeks. YBLI group showed a significant decrease in leptin, leptin:adiponectin ratio, IL-6, 8-OHdG, and TBARS levels, whereas there was a significant incr...Continue Reading

References

Feb 7, 2001·The American Journal of Clinical Nutrition·J E ReselandC A Drevon
May 23, 2001·JAMA : the Journal of the American Medical Association·UNKNOWN Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults
Apr 10, 2003·JAMA : the Journal of the American Medical Association·Katherine EspositoDario Giugliano
Aug 15, 2003·International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity·A S RyanD Elahi
Aug 29, 2003·The Journal of Biological Chemistry·Hui ChenMichael J Quon
Jun 8, 2004·The Journal of Clinical Endocrinology and Metabolism·Erin E Kershaw, Jeffrey S Flier
Jun 8, 2004·The Journal of Clinical Endocrinology and Metabolism·Antonios M XydakisChristie M Ballantyne
May 4, 2005·The Journal of Alternative and Complementary Medicine : Research on Paradigm, Practice, and Policy·Ramesh L BijlaniSushil C Mahapatra
May 6, 2006·Nutrition & Metabolism·Richard J WoodMaria Luz Fernandez
Nov 10, 2007·The American Journal of Clinical Nutrition·Merethe H Rokling-AndersenChristian A Drevon
Mar 29, 2008·Metabolic Syndrome and Related Disorders·Prakash SeshadriNayyar Iqbal
Jan 22, 2011·Nature Reviews. Immunology·Noriyuki OuchiKenneth Walsh
Apr 15, 2011·Diabetes Technology & Therapeutics·Anoop MisraUNKNOWN National Dietary Guidelines Consensus Group
Nov 18, 2011·Menopause : the Journal of the North American Menopause Society·Jeong-Ah LeeDo-Yeon Kim
Jan 31, 2012·Metabolic Syndrome and Related Disorders·Mikael LiljaStefan Söderberg
Jul 27, 2012·The Journal of Alternative and Complementary Medicine : Research on Paradigm, Practice, and Policy·Raj Kumar YadavSushil Chandra Mahapatra
Dec 6, 2012·The Journal of Alternative and Complementary Medicine : Research on Paradigm, Practice, and Policy·Kumar SarvottamSushil C Mahapatra
May 9, 2013·Journal of Obesity·Andrew A Bremer, Ishwarlal Jialal
May 24, 2013·International Journal of Molecular Sciences·Isabella SaviniLuciana Avigliano
Aug 3, 2013·Clinical Nutrition Research·Yun-Jung BaeMi-Kyung Sung
Sep 11, 2013·Reviews in Endocrine & Metabolic Disorders·Michael P Scheid, Gary Sweeney
Jun 12, 2014·Revista da Associação Médica Brasileira·Sílvia Paredes, Laura Ribeiro
Nov 6, 2014·Arquivos brasileiros de endocrinologia e metabologia·Masoud RamezanipourSara Seyed Emami
May 13, 2015·The Journal of Alternative and Complementary Medicine : Research on Paradigm, Practice, and Policy·Shiv Basant KumarRima Dada
Jul 25, 2015·Translational Research : the Journal of Laboratory and Clinical Medicine·Francine K WeltyTarec K Elajami
May 3, 2016·The Journal of Alternative and Complementary Medicine : Research on Paradigm, Practice, and Policy·Rashmi YadavKanwal P Kochar
Nov 1, 2016·Antioxidants & Redox Signaling·Alice Carrier
Apr 25, 2017·The Journal of Alternative and Complementary Medicine : Research on Paradigm, Practice, and Policy·Rashmi YadavRitesh Netam

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Citations

Sep 22, 2020·Journal of Integrative Medicine·Dastan M Khoshnaw, Abhijit A Ghadge
Apr 4, 2021·International Journal of Environmental Research and Public Health·Juana Rosado-PérezVíctor Manuel Mendoza-Núñez
Jun 29, 2021·Annals of Behavioral Medicine : a Publication of the Society of Behavioral Medicine·Rajesh G NairRamesh Mavathur

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