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Comparative electrophysiological effects of Org 6001, a new orally active antidysrhythmic agent, and lignocaine on human ventricular muscle

British Journal of Pharmacology

Jan 1, 1980

Kathleen A Kane

PMID: 7357199

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Abstract

1 The electrophysiological effects of Org 6001, a new orally active antidysrhythmic agent, have been compared with those of lignocaine on the human ventricular action potential in vitro.2 Org 6001 (4 to 16 mg/l) greatly reduced the maximum rate of depolarization (MRD) of the human ventr...read more

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Org 6001
Potassium
Androstanols
17-Ketosteroids
Lidocaine Monohydrochloride, Monohydrate
Cardiac Depressants
Electric Stimulation Technique
Nerve Impulses
Heart
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Comparative electrophysiological effects of Org 6001, a new orally active antidysrhythmic agent, and lignocaine on human ventricular muscle

British Journal of Pharmacology

Jan 1, 1980

Kathleen A Kane

PMID: 7357199

DOI:

Abstract

1 The electrophysiological effects of Org 6001, a new orally active antidysrhythmic agent, have been compared with those of lignocaine on the human ventricular action potential in vitro.2 Org 6001 (4 to 16 mg/l) greatly reduced the maximum rate of depolarization (MRD) of the human ventr...read more

Mentioned in this Paper

Org 6001
Potassium
Androstanols
17-Ketosteroids
Lidocaine Monohydrochloride, Monohydrate

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