Comparative Evaluation of Serum Lipid Profile in Patients with Oral Submucous Fibrosis and Oral Squamous Cell Carcinoma with that of Control Subjects: A Case Control Study

Journal of Pharmacy & Bioallied Sciences
A Cicilia SubbulakshmiS Naveen

Abstract

The aim of the study was to evaluate the serum lipid profile among untreated oral squamous cell carcinoma (OSCC) and oral submucous fibrosis (OSMF) patients. This study was done in three groups of patients - OSMF, OSCC, and control. There are twenty participants in each group. Calorimetric method using semi-autoanalyzer was used for analyzing the lipid levels (cholesterol, triglycerides [TGL], and high-density lipids [HDL]) after collecting 2 ml of fasting blood from these patients. Low-density lipid [LDL] values were obtained by calculator method. There was a significant decrease in serum lipid levels of patients with OSMF and OSCC. The decrease in lipid levels in OSMF and OSCC patients is due to its utilization by the cells during the cancer process.

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Methods Mentioned

BETA
biopsy

Software Mentioned

SPSS

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