Comparative evaluation of the antimicrobial efficacy of a 5% sodium hypochlorite subsonic-activated solution

Journal of Endodontics
Damiano PasqualiniElio Berutti

Abstract

The study evaluated the efficacy of subsonic agitation of sodium hypochlorite (NaOCl) in reducing bacterial load in the root canal. Root canals of 112 extracted human single-root teeth were preflared using K-Flexofiles (Dentsply Maillefer, Ballaigues, Switzerland) up to #20 and then shaped using ProTaper S1-S2-F1-F2-F3 (Dentsply Maillefer) at the working length. Irrigation was performed with 33 mL of 5% NaOCl, alternating with 10 mL of 10% EDTA. After ethylene oxide sterilization, the root canals were infected with 30 microL of Enterococcus faecalis culture and randomly assigned to four groups (n = 25) of different irrigation regimens plus positive and negative controls. Irrigation was performed with 2 mL of 5% NaOCl. In the NaOCl 15 group, the irrigant was left in place for 15 seconds, and in the NaOCl 30 group it was left in place for 30 seconds. In the EndoActivator (EA; Dentsply Tulsa Dental Specialties, Tulsa, OK) 15 and EA 30 groups, NaOCl was subsonically agitated with EA for 15 and 30 seconds, respectively. The residual bacterial count was then evaluated. Differences among groups were analyzed with one-way analysis of variance and the post hoc Bonferroni test (p < 0.05). A statistically significant difference was eviden...Continue Reading

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Citations

Nov 14, 2013·PloS One·Nurit BeythErvin I Weiss
Oct 18, 2011·Journal of Endodontics·Kerstin M GallerGottfried Schmalz
Aug 19, 2011·Journal of Endodontics·Luciana Magrin Blank-GonçalvesManoel Eduardo de Lima Machado
Jul 6, 2011·Dental Clinics of North America·Rory E Mortman
Oct 31, 2012·Letters in Applied Microbiology·N MandrasA M Cuffini
Jul 12, 2019·Journal of Investigative and Clinical Dentistry·Eugenio PedullàSimone Grandini
Jun 13, 2013·International Journal of Immunopathology and Pharmacology·N MandrasA M Cuffini

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