Comparative evaluation of three semi-quantitative radiographic grading techniques for knee osteoarthritis in terms of validity and reproducibility in 1759 X-rays: report of the OARSI-OMERACT task force

Osteoarthritis and Cartilage
L GossecOARSI-OMERACT task force "total articular replacement as outcome measure in OA"

Abstract

The objective of this work was to compare the measurement properties of three categorical X-ray scoring methods of knee osteoarthritis (OA), both on semiflexed and extended views. In data obtained from trials and cohorts, X-rays were graded using Kellgren and Lawrence (KL), the OA Research Society International (OARSI) joint space narrowing score, and measurement of joint space width (JSW). JSW was analyzed as a categorical variable. Construct validity was assessed through logistic regression between X-ray stages and Western Ontario and McMaster Universities OA Index. Inter-observer reliability was assessed in 50 subjects for extended views by weighted kappa. Intra-observer reliability and sensitivity to change were assessed separately for extended and semiflexed views in 50 patients who had both views performed, over a 30-month interval, by weighted kappa and standardized response mean (SRM). Extended views were available from three trials and two cohorts (1759 X-rays), including one trial in which both extended and semiflexed views (antero-posterior) were obtained. Correlation with clinical parameters was low for the three scoring methods, except for the single community-based cohort. Inter-rater reliability was higher for ca...Continue Reading

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Citations

Jan 26, 2013·BMJ : British Medical Journal·Richard B FrobellL Stefan Lohmander
Aug 25, 2012·BMC Musculoskeletal Disorders·Andrew J MetcalfeCarina A Thorstensson
Feb 24, 2009·Arthritis Research & Therapy·David T Felson
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Mar 9, 2012·The Journal of Hand Surgery·Anneluuk LindenhoviusUNKNOWN COAST Collaborative
Aug 12, 2008·Osteoarthritis and Cartilage·L GossecUNKNOWN OARSI-OMERACT task force "total articular replacement as outcome measure in OA"
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