PMID: 6170291Aug 1, 1981Paper

Comparative genetics of hamster amylases

Biochemical Genetics
W D Dawson, L L Huang

Abstract

Syrian (Mesocricetus auratus) and Chinese (Cricetulus griseus) hamsters were phenotyped by electrophoresis for salivary and pancreatic amylases. Syrian hamsters possess two salivary amylase electromorphs, the more anodal (fast) being invariant in 250 outbred and 17 representatives of 5 highly inbred lines. The slow electromorph had activity equal to that of the fast amylase (heavy), or had distinctly less activity (light), or was absent (null). The slow electromorph is inherited as an autosomal semidominant trait with two alleles. Amys and Amyo. Amys homozygotes produce heavy, Amyo homozygotes null, and heterozygotes light phenotypes, respectively. Five inbred strains of hamsters were homozygous Amyo. Pancreatic amylase was monomorphic. Eight outbred Chinese hamsters showed no salivary amylase activity with electrophoresis, but slight activity with long incubation on starch-agar plates. However, pancreatic amylase activity in the Chinese hamster exceeded that in Syrian hamsters. Site duplication and apparent "null" alleles for amylase genes occur in muroid rodents. The evolutionary implications are discussed.

References

Sep 1, 1977·The Journal of Heredity·M G EvansW D Dawson
Oct 25, 1972·Nature: New Biology·A D MerrittJ C Ward
Jan 4, 1972·Biochemistry·T G Sanders, W J Rutter
May 1, 1973·The Journal of Heredity·R D KaplanF H Ruddle
Apr 1, 1980·Biochemical Genetics·J P HjorthJ T Nielsen

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Citations

Jan 1, 1992·Genetica·D M Robins, L C Samuelson
May 21, 2009·Evolution; International Journal of Organic Evolution·Suzanne EdmandsAnnmarie S Hwang
Jul 1, 2006·Journal of Clinical Pharmacology·Robert J StrakaMichael Y Tsai
Jun 14, 2006·Trends in Ecology & Evolution·Ilik Saccheri, Ilkka Hanski
Oct 1, 1994·Journal of Dental Research·F A ScannapiecoR O Wadenya

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