Comparative Genomic Analysis Reveals the Potential Risk of Vibrio parahaemolyticus Isolated From Ready-To-Eat Foods in China

Frontiers in Microbiology
Rui PangXiaojuan Yang

Abstract

Vibrio parahaemolyticus is a major foodborne pathogen associated with the consumption of aquatic products. The presence of this bacterium in ready-to-eat (RTE) foods has recently been reported. However, the genomic features and potential risks of V. parahaemolyticus isolated from RTE foods are poorly understood. To help understand the genome-wide characteristics of RTE food isolates, the complete genomes of 27 RTE food isolates were sequenced and compared to those of 20 clinical and 19 other environmental (e.g., water and aquatic product source) isolates using a comparative genomics approach. Analysis revealed that V. parahaemolyticus RTE food isolates had higher numbers of genes on average and possessed more accessory genes than isolates from other sources. Most RTE food isolates were positive for some known virulence-associated genes and pathogenicity islands (PAIs), and some of these isolates were genetically homologous to clinical isolates. Genome-wide association analysis revealed 79 accessory genes and 78 missense single-nucleotide polymorphisms that affected 11 protein-coding genes were significantly associated with RTE food sources. These genes were mostly involved in defense mechanisms and energy production and convers...Continue Reading

References

Aug 1, 1990·Applied and Environmental Microbiology·A DePaolaR M McPhearson
Oct 27, 2004·Infection and Immunity·Kwon-Sam ParkTakeshi Honda
May 5, 2006·BMC Genomics·Catherine C HurleyE Fidelma Boyd
Jan 16, 2007·Clinical Microbiology Reviews·G Balakrish NairDavid A Sack
Nov 13, 2008·Journal of Bioscience and Bioengineering·Hiromi KubotaHiroo Uchiyama
Mar 13, 2010·PloS One·Morgan N PriceAdam P Arkin
Apr 23, 2010·Archives of Microbiology·Tobias Schweinitzer, Christine Josenhans
Jun 5, 2010·Journal of Applied Microbiology·R Van Houdt, C W Michiels
Jul 26, 2011·Microbes and Infection·Christopher A BrobergKim Orth
Apr 18, 2012·Journal of Computational Biology : a Journal of Computational Molecular Cell Biology·Anton BankevichPavel A Pevzner
Apr 27, 2012·Journal of Clinical Microbiology·Jessica L JonesAngelo DePaola
Oct 12, 2012·Journal of Clinical Microbiology·Donatella OttavianiAntonio Carraturo
Feb 15, 2013·Molecular Biology and Evolution·Lu ChengJukka Corander
Mar 8, 2013·Genome Announcements·Roderick V JensenAnn M Stevens
Oct 30, 2013·Current Microbiology·Iram LiaqatRobert G J Edyvean
Jan 1, 2014·Frontiers in Cellular and Infection Microbiology·Daniela CeccarelliRita R Colwell
Mar 20, 2014·Bioinformatics·Torsten Seemann
Jun 14, 2014·Proceedings of the National Academy of Sciences of the United States of America·Dor SalomonKim Orth
Feb 18, 2015·Frontiers in Microbiology·Vengadesh LetchumananKok-Gan Chan
Apr 1, 2015·Nature Communications·Lucy A WeinertUNKNOWN BRaDP1T Consortium
Apr 9, 2015·Frontiers in Microbiology·Tracy H HazenPatricia A Sobecky
Jul 23, 2015·Bioinformatics·Andrew J PageJulian Parkhill
Nov 27, 2016·Genome Biology·Ola BrynildsrudVegard Eldholm
Aug 10, 2017·Frontiers in Microbiology·Romilio T EspejoNicolas Plaza

❮ Previous
Next ❯

Datasets Mentioned

BETA
PRJNA491373

Methods Mentioned

BETA
PCR
environmental stresses

Software Mentioned

iTOL
Harvesttools
Parsnp
PhiPack
BAPS
Prokka
BLAST
SnpEff
PLINK
FastTree

Related Concepts

Related Feeds

CRISPR & Staphylococcus

CRISPR-Cas system enables the editing of genes to create or correct mutations. Staphylococci are associated with life-threatening infections in hospitals, as well as the community. Here is the latest research on how CRISPR-Cas system can be used for treatment of Staphylococcal infections.

Biofilms

Biofilms are adherent bacterial communities embedded in a polymer matrix and can cause persistent human infections that are highly resistant to antibiotics. Discover the latest research on Biofilms here.