Comparative genomic hybridization for genetic analysis of renal oncocytomas

Genes, Chromosomes & Cancer
J C PrestiF M Waldman

Abstract

Renal oncocytomas are uncommon tumors of the kidney that are considered to be of low malignant potential. Neither conventional cytogenetic nor restriction fragment length polymorphism analyses have identified consistent genetic alterations in their genomic DNA. The purpose of the present study was to identify the genetic alterations associated with the development of renal oncocytomas. We studied 13 renal oncocytomas by using comparative genomic hybridization, and we identified loss of genetic material from chromosomes 1 and/or 14 in six of these tumors. These alterations may represent early genetic events in the development of these tumors.

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Citations

Jul 14, 1999·The American Journal of Surgical Pathology·L J MedeirosJ B Beckwith
Sep 21, 2013·Journal of Translational Medicine·Amin El-HeliebiCarolin Lackner
Jun 23, 2012·Seminars in Cancer Biology·Holger Moch
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Oct 17, 2009·International Journal of Urology : Official Journal of the Japanese Urological Association·Antonio Lopez-BeltranLiang Cheng
Jul 2, 2010·International Journal of Urology : Official Journal of the Japanese Urological Association·Maria V Yusenko
Jan 10, 2004·The Journal of Urology·Valerie LindgrenMaria M Picken
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Dec 13, 2005·Cancer Genetics and Cytogenetics·Marta SalidoFrancesc Solé
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Jul 5, 2005·Cancer Genetics and Cytogenetics·László FüzesiBastian Gunawan
Apr 26, 2005·Clinics in Laboratory Medicine·Timothy D JonesLiang Cheng
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May 7, 2002·Urology·Debby H ChaoArie S Belldegrun
Jun 20, 2002·Cancer Genetics and Cytogenetics·Stéphanie StruskiPascale Cornillet-Lefebvre
Apr 13, 2001·Archives of Pathology & Laboratory Medicine·X LeroyB Gosselin

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