Comparative in vitro activity of 11 beta-lactam antibiotics against 91 Staphylococcus intermedius strains isolated from staphylococcal dermatitis in dogs

Zentralblatt für Veterinärmedizin. Reihe B. Journal of veterinary medicine. Series B
S PirizS Vadillo

Abstract

A study was made of the susceptibility of 91 strains of Staphylococcus intermedius, isolated from staphylococcal dermatitis of dogs, to 11 beta-lactam antimicrobial agents. The activity of these antimicrobial agents against all strains was tested at pH 7.2 and 8.5. Finally, a comparative study was made of the susceptibility of these micro-organisms, dividing them into six groups: beta-lactamase positive and negative, methicillin resistant and susceptible and oxacillin resistant and susceptible. Only three of the 11 antimicrobial agents studied exhibited satisfactory behaviour at the two pH levels studied: mezlocillin, cefazolin and cefalotine. There was a good correlation at pH 8.5 between methicillin-resistant strains and those resistant to penicillin G, ampicillin, amoxycillin, cefamandole and cefuroxime. This correlation was not observed, however, between oxacillin-resistant strains and strains resistant to the other antimicrobial agents studied.

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Citations

Nov 28, 2006·Research in Veterinary Science·Tomasz Hauschild, Agnieszka Wójcik
May 7, 2005·Journal of Veterinary Medicine. B, Infectious Diseases and Veterinary Public Health·T J KimJ I Lee
Dec 20, 2002·Journal of Veterinary Medicine. B, Infectious Diseases and Veterinary Public Health·M T Tejedor Junco, J L Martín Barrasa
Apr 20, 2001·The Journal of Veterinary Medical Science·A ShimizuM Takagi
Sep 18, 2015·Journal of Clinical Microbiology·Kristina KadlecJ Scott Weese
Mar 10, 1999·The Veterinary Record·J TomlinP Muir

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