PMID: 11328784May 1, 2001Paper

Comparative in vitro activity of the new quinolone gemifloxacin (SB-265805) with other fluoroquinolones against respiratory tract pathogens

The Journal of Antimicrobial Chemotherapy
F García-GarroteE Bouza

Abstract

The in vitro activity of gemifloxacin (SB-265805) was compared with that of other fluoroquinolones against 302 clinical isolates of Streptococcus pneumoniae, 300 clinical isolates of Haemophilus influenzae and 28 clinical isolates of Moraxella catarrhalis, including multiply resistant strains. Gemifloxacin at 0.12 mg/L inhibited all microorganisms tested. MIC(90) values of gemifloxacin, trovafloxacin, grepafloxacin and levofloxacin against all (630) isolates tested were 0.03, 0.12, 0.12 and 1 mg/L, respectively. MIC(90) values of the same fluoroquinolones against S. pneumoniae were 0.06, 0.25, 0.12 and 1 mg/L, respectively.

Citations

Jul 18, 2003·Current Infectious Disease Reports·Philippe Cottagnoud, Martin G. Täuber
Aug 17, 2002·Antimicrobial Agents and Chemotherapy·Hee-Jeong YunEung-Chil Choi
Jun 20, 2007·Scandinavian Journal of Infectious Diseases·Marianne LindgrenOlli Meurman

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