Comparative Incidence of Conformational, Neurodegenerative Disorders

PloS One
Jesús de Pedro-CuestaMiguel Calero

Abstract

The purpose of this study was to identify incidence and survival patterns in conformational neurodegenerative disorders (CNDDs). We identified 2563 reports on the incidence of eight conditions representing sporadic, acquired and genetic, protein-associated, i.e., conformational, NDD groups and age-related macular degeneration (AMD). We selected 245 papers for full-text examination and application of quality criteria. Additionally, data-collection was completed with detailed information from British, Swedish, and Spanish registries on Creutzfeldt-Jakob disease (CJD) forms, amyotrophic lateral sclerosis (ALS), and sporadic rapidly progressing neurodegenerative dementia (sRPNDd). For each condition, age-specific incidence curves, age-adjusted figures, and reported or calculated median survival were plotted and examined. Based on 51 valid reported and seven new incidence data sets, nine out of eleven conditions shared specific features. Age-adjusted incidence per million person-years increased from ≤1.5 for sRPNDd, different CJD forms and Huntington's disease (HD), to 1589 and 2589 for AMD and Alzheimer's disease (AD) respectively. Age-specific profiles varied from (a) symmetrical, inverted V-shaped curves for low incidences to (b)...Continue Reading

References

Mar 1, 1992·Journal of Neurology, Neurosurgery, and Psychiatry·A J HughesA J Lees
Aug 1, 1991·Archives of Neurology·E GranieriP De Bastiani
Nov 1, 1983·American Journal of Epidemiology·D W Anderson, N Mantel
Mar 22, 1997·Lancet·R G WillP G Smith
May 11, 2000·Annals of Neurology·R G WillR S Knight
Jul 11, 2001·Neurobiology of Aging·A RuitenbergM M Breteler
Mar 29, 2002·Movement Disorders : Official Journal of the Movement Disorder Society·Luis Erik ClaveríaJesús de Pedro-Cuesta
Sep 21, 2002·Proceedings of the National Academy of Sciences of the United States of America·Lihua Y MarmorsteinAlan D Marmorstein
Oct 11, 2002·Archives of Neurology·Steven D EdlandEmre Kokmen
Dec 6, 2002·The American Journal of Pathology·Oskar KoperekGeorg Wick
Mar 10, 2004·Neurology·J Benito-LeónUNKNOWN Neurological Disorders in Central Spain (NEDICES) Study Group
Jun 12, 2004·Current Atherosclerosis Reports·José A Luchsinger, Richard Mayeux
May 25, 2005·Neurology·Julián Benito-LeónUNKNOWN Neurological Disorders in Central Spain (NEDICES) Study Group
Jul 1, 2005·Current Neurology and Neuroscience Reports·K Ray ChaudhuriP Martinez-Martin
Mar 10, 2007·Nature Reviews. Drug Discovery·Leslie M ShawJohn Q Trojanowski
Oct 20, 2007·American Journal of Epidemiology·Fang FangUnnur Valdimarsdóttir
Feb 11, 2009·Archives of Neurology·Keith A JosephsRonald C Petersen
Apr 15, 2009·Archives of Neurology·Fang FangWeimin Ye
May 19, 2009·Prion·Bess Frost, Marc I Diamond
Apr 15, 2010·Neuroepidemiology·Kyle SteenlandAllan Levey
Oct 1, 2010·Neuroepidemiology·Yen-Yu Chen, Chien-Hsu Lai
Jan 26, 2011·Journal of Alzheimer's Disease : JAD·Alex E RoherThomas G Beach
Mar 29, 2011·Progress in Retinal and Eye Research·Kyoko Ohno-Matsui
Aug 10, 2011·Archives of Neurology·Joshua A SonnenThomas J Montine
Aug 16, 2011·Brain : a Journal of Neurology·James R BurrellJohn R Hodges
Sep 23, 2011·Journal of Neuropathology and Experimental Neurology·Karen S SantaCruzSuzanne L Tyas
Oct 18, 2011·Journal of Neuropathology and Experimental Neurology·Heiko BraakKelly Del Tredici
Jan 25, 2012·Journal of Neuro-oncology·Fonnet E BleekerSieger Leenstra
Feb 15, 2012·The British Journal of Ophthalmology·Christopher G OwenAlicja R Rudnicka
Mar 6, 2012·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·Carlo RinaldiGiuseppe De Michele
Jun 1, 2012·The New England Journal of Medicine·John Hardy, Tamas Revesz
Aug 15, 2012·Nature Reviews. Neurology·Johnathan Cooper-KnockPamela J Shaw
Sep 12, 2012·Archives of Neurology·Zhengrui XiEkaterina Rogaeva
Sep 27, 2012·Journal of Alzheimer's Disease : JAD·Javier OlazaránUNKNOWN AD Research Unit Investigators
Oct 2, 2012·Alzheimer Disease and Associated Disorders·Berneet KaurJohn M Olichney
Dec 4, 2012·Brain : a Journal of Neurology·Mark YarchoanSteven E Arnold
Jul 24, 2013·Trends in Neurosciences·Jason D WarrenMartin N Rossor
Aug 3, 2013·Rambam Maimonides Medical Journal·Efrat KravitzMichal Schnaider Beeri
Nov 28, 2013·Annual Review of Genetics·Stanley B Prusiner

❮ Previous
Next ❯

Citations

Mar 1, 2016·Journal of Alzheimer's Disease : JAD·Jesús de Pedro-CuestaMiguel Calero
Aug 11, 2016·Neurodegenerative Disease Management·Sheharyar Sajjad BaigOliver Wj Quarrell
Apr 3, 2016·Brain Research·Navit Ogen-ShternGerardo Z Lederkremer
Mar 23, 2017·Neurología : publicación oficial de la Sociedad Española de Neurología·A Robles Bayón, F Gude Sampedro
Jul 22, 2018·Frontiers in Neuroscience·Alexandra Moreno-GarcíaMiguel Calero
Apr 4, 2019·Molecular Neurobiology·Eliana Baez-JuradoGeorge E Barreto
Jan 21, 2021·Antioxidants·Alexandra Moreno-GarcíaOlga Calero

❮ Previous
Next ❯

Software Mentioned

PAQUID
NEDICES

Related Concepts

Related Feeds

Amyloid Lateral Sclerosis

Amyotrophic Lateral Sclerosis (ALS) is a progressive nervous system disease associated with the death of neurons that control voluntary muscles. Discover the latest research on ALS here.

ALS: Genetics

Amyotrophic Lateral Sclerosis (ALS) is a progressive neurodegenerative disorder characterized by muscle weakness. ALS is a genetically heterogeneous disorder with several causative genes. Here are the latest discoveries pertaining to the genetics of this disease.

Alzheimer's Disease: Amyloid Beta

Alzheimer's disease is a neurodegenerative disease associated with the accumulation of amyloid plaques in the brain; these plaques are comprised of amyloid beta deposits. Here is the latest research in this field.

Alzheimer's Disease: APP

Amyloid precursor protein (APP) proteolysis is critical for the development of Alzheimer's disease, a neurodegenerative disease associated with accumulation of amyloid plaques in the brain. Here is the latest research on APP and Alzheimer's disease.

ALS: Prions

Prions are misfolded proteins which characterize several fatal neurodegenerative diseases. Prion-like mechanisms are associated with the pathogenesis of Amyotrophic Lateral Sclerosis (ALS). Here is the latest research on ALS and prions.

Alzheimer's Disease: Tau & TDP-43

Alzheimer's disease is a neurodegenerative disease. This feed focuses on the underlying role of tau proteins and TAR DNA-binding protein 43, as well as other genetic factors, in Alzheimer's disease.

ALS: Genetics

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder characterized by muscle weakness. Here is the latest research investigating genetic alterations in this genetically heterogeneous disorder.

Bovine Spongiform Encephalopathy

Bovine spongiform encephalopathy is a neurodegenerative disease belonging to the transmissible spongiform encephalopathies, a group of diseases including sheep scrapie and human Creutzfeldt-Jakob disease. Here is the latest research.

Epidemiology of Aging

This feed focuses on epidemiology of aging and aging-related conditions, including Alzheimer’s disease, dementia, and age-associated cognitive impairment. Here is the latest research.

Bovine Spongiform Encephalopathy (MDS)

Bovine spongiform encephalopathy is a neurodegenerative disease belonging to the transmissible spongiform encephalopathies, a group of diseases including sheep scrapie and human Creutzfeldt-Jakob disease. Here is the latest research.

Related Papers

Journal of Neurology, Neurosurgery, and Psychiatry
Matthew C Kiernan
Alzheimer's & Dementia : the Journal of the Alzheimer's Association
Sharon X XieJohn Q Trojanowski
Seminars in Neurology
Shannon L Risacher, Andrew J Saykin
© 2021 Meta ULC. All rights reserved