Abstract
Inbred Balb/c mice were infected with three clones of Trypanosoma congolense (Sam.28.1, Dind.3.1 and K60.1A) corresponding, respectively, to the three genetically distinct types (savannah, forest and kilifi) defined within this species, for the purpose of comparing their pathogenicity for a better understanding of the epidemiology of African trypanosomosis. Another clone of savannah type, IL 3000, was also tested simultaneously to study a probable strain variation. Both the clones of savannah type were found of extreme virulence with loss of appetite, rough hair, rapid respiration, lethargy, and all mice died within a week. Parasitaemias evolved rapidly to the first peak by day 3-5 post-inoculation without any remission and the course of disease was correlated positively with the prepatent period. The clones of the forest type and the kilifi type were of low virulence with chronic infection and symptoms progressively less patent throughout the infection; only one mouse died in each experimental group.
References
Feb 1, 1977·Tropical Animal Health and Production·A G Luckins
Dec 1, 1976·Experimental Parasitology·W J Herbert, W H Lumsden
Nov 1, 1992·International Journal for Parasitology·D K MasigaW C Gibson
Jul 1, 1991·Parasite Immunology·R W PalingD J Williams
Apr 1, 1987·Parasitology·R A MasakeK Nguli
Jun 1, 1988·Parasitology·J K GashumbaD G Godfrey
May 1, 1987·Parasite Immunology·G E Roelants, M Pinder
Dec 1, 1970·Experimental Parasitology·S M Lanham, D G Godfrey
Apr 1, 1984·Experimental Parasitology·M Pinder
Feb 1, 1993·Parasitology·P A MajiwaE Zweygarth
Aug 1, 1997·Veterinary Parasitology·J M ReifenbergG Cuny
Citations
Aug 23, 2002·Veterinary Parasitology·Z BengalyL Sawadogo
May 25, 2006·Parasitology·J MasumuP van den Bossche
May 25, 2012·BMC Veterinary Research·John KatereggaAlain François Vincent Boulangé
May 17, 2011·Parasites & Vectors·Bashir SalimChihiro Sugimoto
Oct 3, 2012·Parasites & Vectors·Jesca NakayimaChihiro Sugimoto
Dec 4, 2009·PLoS Neglected Tropical Diseases·Liam J MorrisonAnnette MacLeod
Jan 1, 2011·African Journal of Traditional, Complementary, and Alternative Medicines : AJTCAM·N E NwezeI U Asuzu
May 17, 2011·Veterinary Parasitology·Andy TaitAnnette Macleod
Jan 6, 2011·Parasite Immunology·P Van den BosscheV Delespaux
Mar 7, 2006·International Journal for Parasitology·J MasumuP Van den Bossche
Feb 1, 2014·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Adriana C RodriguesMarta M G Teixeira
Mar 17, 2009·International Journal for Parasitology·Pascal GrébautPhilippe Holzmuller
Oct 23, 2016·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Geraldine BossardPhilippe Holzmuller
Oct 11, 2016·Parasitology·Federica GiordaniMichael P Barrett
Apr 2, 2015·PloS One·Haripriya RanganDaniel J Murphy
Feb 2, 2017·Parasite : Journal De La Société Française De Parasitologie·Gaël Darren MagangaBenjamin Ollomo
Feb 17, 2015·The Onderstepoort Journal of Veterinary Research·Makhosazana Y MotloangAbdalla A Latif
Jul 13, 2017·The Onderstepoort Journal of Veterinary Research·Purity K GitongaJohn K Thuita
Jul 29, 2017·Molecular Ecology·Eliane TihonFrederik Van den Broeck
Dec 19, 2008·Critical Reviews in Food Science and Nutrition·F J ChadareM A J S Van Boekel
Sep 19, 2018·Proceedings of the National Academy of Sciences of the United States of America·George R YoungJonathan P Stoye
Oct 17, 2015·Royal Society Open Science·Karen L BellDaniel J Murphy
Oct 11, 2019·Royal Society Open Science·Anna ChládováBohdan Lojka
Jun 21, 2019·PloS One·Kariuki NdunguJohn Thuita
Oct 16, 2019·Parasites & Vectors·Judith Sophie WeberSørge Kelm
Feb 11, 2014·The Journal of Immunology : Official Journal of the American Association of Immunologists·George Kassiotis
Feb 5, 2015·Food Science & Nutrition·Traoré HyacintheBréhima Diawara
Jun 8, 2019·Veterinary Parasitology: X·Roger Ramirez-BarriosPhilippe Holzmuller