Comparative Pathology and Pathogenesis of African Swine Fever Infection in Swine

Frontiers in Veterinary Science
Francisco J Salguero

Abstract

African Swine Fever (ASF) is a viral disease that affects animals of the Suidae family, and soft ticks from the genus Ornithodoros can also be infected by the ASF virus (ASFV). The disease was first described in Africa at the beginning of the twentieth century as an acute disease characterized by high mortality and fatal hemorrhages. ASF has caused outbreaks in numerous countries and it continues to be devastating nowadays for the porcine sector in those countries affected, and a massive threat for those free of the disease. ASF can follow clinical courses from peracute to chronic in domestic pigs (Sus scrofa) depending on a variety of factors, including the immune status of the animals and the virulence of the ASFV strain. The key features of the pathogenesis of the disease in domestic swine are a) a severe lymphoid depletion including lymphopenia and a state of immunodeficiency, and b) hemorrhages. However, African wild swine like bushpigs (Potamochoerus larvatus), red river hogs (Potamochoerus porcus), and warthogs (Phacochoerus africanus) can be infected by ASFV showing no clinical signs of disease and acting as natural reservoir hosts. In this article we review the key features of the gross and microscopic pathology togeth...Continue Reading

References

Jan 1, 1978·The Journal of General Virology·R C Wardley, P J Wilkinson
Jun 16, 1992·Annals of the New York Academy of Sciences·F C Alexander
Oct 1, 1990·Virus Research·A AlcamíE Viñuela
Mar 1, 1989·Veterinary Pathology·M A SierraJ M Sanchez-Vizcaino
Jun 1, 1987·Veterinary Microbiology·L M SwaneyA Orfei
Jan 1, 1988·Advances in Virus Research·C A Mebus
May 2, 1987·The Veterinary Record·P BirontJ Leunen
Sep 1, 1987·Veterinary Pathology·M A SierraA Jover
Jan 1, 1972·Journal of Comparative Pathology·A Greig
Jan 1, 1970·Archiv für die gesamte Virusforschung·W PlowrightJ Parker
Feb 2, 1980·The Veterinary Record·P J WilkinsonR S Johnston
Sep 1, 1995·The Journal of General Virology·J C Gómez-VillamandosM A Sierra
Jan 1, 1993·Archives of Virology·C J VilledaE Viñuela
Sep 1, 1995·Research in Veterinary Science·J C Gómez-VillamandosP J Wilkonson
Jan 1, 1996·Veterinary Research Communications·J HervásM A Sierra
Nov 1, 1996·Research in Veterinary Science·L CarrascoM A Sierra
Nov 1, 1996·Journal of Comparative Pathology·J C Gómez-VillamandosM A Sierra
Mar 1, 1997·Veterinary Pathology·J C Gómez-VillamandosM A Sierra
May 1, 1997·Research in Veterinary Science·L CarrascoP J Wilkinson
Jun 20, 1998·The Journal of General Virology·C A OuraR M Parkhouse
Jun 20, 1998·The Journal of General Virology·C A OuraR M Parkhouse
Sep 2, 1998·The Veterinary Record·J PérezJ Martín de las Mulas
Oct 31, 2002·Veterinary Immunology and Immunopathology·F J SalgueroJ C Gómez-Villamandos
Mar 15, 2003·Veterinary Pathology·J C Gomez-VillamandosM A Sierra
Jun 14, 2003·TheScientificWorldJournal·Laszlo Zsak, John G Neilan
Jan 1, 2004·Histology and Histopathology·F J SalgueroJ C Gómez-Villamandos
May 17, 2005·Journal of Comparative Pathology·F J SalgueroJ C Gómez-Villamandos
Jun 9, 2006·The Journal of General Virology·Afonso P BastoCarlos Martins

❮ Previous
Next ❯

Citations

Dec 8, 2020·Veterinary World·Sharanagouda S PatilParimal Roy
Jan 6, 2021·Porcine Health Management·Agnès Waret-SzkutaGuy-Pierre Martineau
Feb 19, 2021·Transboundary and Emerging Diseases·Ellen Mighell, Michael P Ward
May 1, 2021·Pathogens·Ebanja Joseph EbwangaJan Paeshuyse
Aug 27, 2021·Veterinary Sciences·Georgia D BrellouEleni D Tzika
Oct 1, 2021·Transboundary and Emerging Diseases·Gustavo MachadoCristina Lanzas

❮ Previous
Next ❯

Methods Mentioned

BETA
transmission electron microscopy

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Sheng wu gong cheng xue bao = Chinese journal of biotechnology
Jianlin LeiYingqiang Wang
Sheng wu gong cheng xue bao = Chinese journal of biotechnology
Tao WangHua-Ji Qiu
Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences
Solenne CostardLinda K Dixon
© 2022 Meta ULC. All rights reserved