Comparative Principles for Next-Generation Neuroscience

Frontiers in Behavioral Neuroscience
Cory T MillerPartha Mitra

Abstract

Neuroscience is enjoying a renaissance of discovery due in large part to the implementation of next-generation molecular technologies. The advent of genetically encoded tools has complemented existing methods and provided researchers the opportunity to examine the nervous system with unprecedented precision and to reveal facets of neural function at multiple scales. The weight of these discoveries, however, has been technique-driven from a small number of species amenable to the most advanced gene-editing technologies. To deepen interpretation and build on these breakthroughs, an understanding of nervous system evolution and diversity are critical. Evolutionary change integrates advantageous variants of features into lineages, but is also constrained by pre-existing organization and function. Ultimately, each species' neural architecture comprises both properties that are species-specific and those that are retained and shared. Understanding the evolutionary history of a nervous system provides interpretive power when examining relationships between brain structure and function. The exceptional diversity of nervous systems and their unique or unusual features can also be leveraged to advance research by providing opportunities ...Continue Reading

References

Sep 21, 1979·Proceedings of the Royal Society of London. Series B, Containing Papers of a Biological Character·S J Gould, R C Lewontin
Jul 15, 1977·Science·S T Emlen, L W Oring
Jun 1, 1976·The Quarterly Review of Biology·J L Gould
Jan 1, 1991·Brain, Behavior and Evolution·H J Karten
Jul 13, 1990·Science·P H Harvey, J R Krebs
Nov 8, 1994·Proceedings of the National Academy of Sciences of the United States of America·A M MurrayJ N Joyce
May 16, 1998·Proceedings of the National Academy of Sciences of the United States of America·G G Rosenthal, C S Evans
Jul 3, 1998·Cerebral Cortex·S M Williams, P S Goldman-Rakic
Jan 29, 2000·Nucleic Acids Research·D B SparrowT J Mohun
Aug 10, 2000·Novartis Foundation Symposium·L A Krubitzer
May 11, 2001·Nature·D A ClarkS S Wang
Mar 19, 2003·Proceedings. Biological Sciences·Robert A BartonRichard Grenyer
Jun 5, 2003·Proceedings of the National Academy of Sciences of the United States of America·Christoph StosiekArthur Konnerth
Feb 3, 2005·Nature Reviews. Neuroscience·Erich D JarvisUNKNOWN Avian Brain Nomenclature Consortium
Jul 20, 2005·Current Opinion in Neurobiology·Leah Krubitzer, Jon Kaas
Aug 24, 2005·Nature Neuroscience·Edward S BoydenKarl Deisseroth
Feb 3, 2006·Annals of Neurology·Victoria E O'CollinsDavid W Howells
Dec 7, 2006·Biology Letters·Karin Isler, Carel P van Schaik
Jan 8, 2009·Frontiers in Neuroanatomy·Paul R MangerGoran Strkalj
Jan 23, 2009·Nature Methods·Marco MankOliver Griesbeck
Mar 28, 2009·Proceedings. Biological Sciences·Nicholas James Strausfeld
May 19, 2009·Trends in Neurosciences·Emrah DüzelPhilippe N Tobler
May 30, 2009·Nature·Erika SasakiTatsuji Nomura
Apr 30, 2010·Frontiers in Integrative Neuroscience·Stephen V Shepherd
Aug 13, 2010·The American Naturalist·Karin GrossHansjoerg P Kunc
Oct 22, 2010·Molecular Biology and Evolution·Stephen H MontgomeryNicholas I Mundy
Mar 1, 1995·Trends in Ecology & Evolution·K Shaw
Mar 11, 2011·Nature·Davi D BockR Clay Reid
Jun 22, 2011·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Paul S Katz
Jan 10, 2012·Current Opinion in Neurobiology·Moritz Helmstaedter, Partha P Mitra
Mar 3, 2012·Evolution; International Journal of Organic Evolution·Stephen H Montgomery, Nicholas I Mundy
Nov 12, 1986·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·J G WhiteS Brenner
May 25, 2012·Nature·Misha B AhrensRuben Portugues
Jun 23, 2012·Proceedings of the National Academy of Sciences of the United States of America·Leah A Krubitzer, Adele M H Seelke
Sep 4, 2012·Genes, Brain, and Behavior·S H Montgomery, N I Mundy
Oct 3, 2012·Proceedings of the National Academy of Sciences of the United States of America·Jennifer Dugas-FordClifton W Ragsdale
Jan 8, 2013·Nature Neuroscience·Lindsey L GlickfeldR Clay Reid
Jan 12, 2013·Current Biology : CB·Harvey J Karten
Mar 14, 2013·Development, Growth & Differentiation·Chiyo TakagiNaoto Ueno

❮ Previous
Next ❯

Citations

Dec 10, 2019·PLoS Biology·Hristos S CourellisCory T Miller
Jun 5, 2020·Neuroscience and Biobehavioral Reviews·Lisa A WilliamsZanna Clay
Jun 23, 2020·Neuroscience and Biobehavioral Reviews·Ajay S MathuruSerafino Teseo
Jul 21, 2021·Microscopy·Alice M StamatakisKunal K Ghosh
Jun 12, 2021·Integrative and Comparative Biology·Jessleen K KanwalSara Wasserman

❮ Previous
Next ❯

Methods Mentioned

BETA
transgenic
electron microscopy
light microscopy

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

© 2022 Meta ULC. All rights reserved