PMID: 3761002Aug 1, 1986Paper

Comparative studies of selenium-75 (selenite and selenomethionine) absorption from various milk diets in suckling rats

The Journal of Nutrition
M H RaghibO M Rennert

Abstract

Selenium (Se) absorption was studied in human milk, bovine milk and infant formula (Similac) using suckling rats as a model. The effect of age on Se absorption from the three milk diets extrinsically labeled with 75Se, either as selenite or selenomethionine, was also investigated. Milk diets were fed by gastric intubation and the radioactivity in the carcass, gastrointestinal tract and the liver were measured 3 h after feeding. There was no difference in [75Se]selenite absorption from the three milk diets between 8-20 d of age. However, significantly higher quantity of 75Se was absorbed from all three milk diets by 20-d-old rats than by the younger rats (46 vs. 32%). This increase in [75Se]selenite absorption with advancing age is opposite to what has been found for most other trace elements. When rats were fed milk diets labeled with [75Se]selenomethionine, the absorption of 75Se was approximately twofold higher in all age groups compared with 75Se absorption from selenite. No difference in [75Se]selenomethionine absorption existed among the three milk diets in 8- or 10-d-old suckling rats. However, at 15 d of age [75Se]selenomethionine absorption from human milk was higher (82%) than from either bovine milk (72%) or infant fo...Continue Reading

Citations

Dec 25, 2007·FEBS Letters·Dennis Ganyc, William T Self
Nov 12, 2002·The British Journal of Nutrition·Jose G Dorea
Jun 1, 2003·Nutrition Research Reviews·Graham LyonsRobin Graham
Sep 17, 2011·The Journal of Reproduction and Development·Fátima NogalesOlimpia Carreras
Feb 24, 2001·Pharmacological Research : the Official Journal of the Italian Pharmacological Society·H D FrancescatoM D Bianchi

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