Comparative study between 68 Ga-prostate-specific membrane antigen positron emission tomography and conventional imaging in the initial staging of prostate cancer.

Journal of Medical Imaging and Radiation Oncology
Hui Sze WongJoe H Chang

Abstract

The management of prostate cancer has undergone significant advances since the introduction of 68 Ga-prostate-specific membrane antigen (68 Ga-PSMA) positron emission tomography (PET) scans. Data on the use of 68 Ga-PSMA PET scans in the setting of biochemical recurrence is widely available. Data on the use of 68 Ga-PSMA PET as an initial staging modality, however, is limited. The aim of this retrospective study was to compare the staging of patients with newly diagnosed prostate cancer between 68 Ga-PSMA PET and current conventional imaging modalities. The potential impact of any change in stage will be analysed. Details of all patients who underwent 68 Ga-PSMA PET in South Australia between March 2016 and March 2017 were obtained. One hundred and thirty-one patients with newly diagnosed prostate cancer who had 68 Ga-PSMA PET prior to consideration of definitive treatment were included in this study. The stage pre-68 Ga-PSMA PET (based on conventional imaging) and post-68 Ga-PSMA PET was recorded. The stage was classified as A - localised disease, B - presence of regional lymphadenopathy, C - oligometastatic disease (up to three metastases) and D - widespread metastases. Management plans were recorded. This study showed that t...Continue Reading

References

Mar 15, 2000·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·A V D'AmicoJ P Richie
Sep 25, 2007·European Journal of Nuclear Medicine and Molecular Imaging·B J KrauseM Schwaiger
Sep 20, 2008·Pathology Oncology Research : POR·Sebastian MannweilerGabor Mehes
Feb 1, 2011·International Journal of Radiation Oncology, Biology, Physics·Barbara Alicja Jereczek-FossaRoberto Orecchia
Sep 28, 2013·European Journal of Nuclear Medicine and Molecular Imaging·Ali Afshar-OromiehUwe Haberkorn
Dec 11, 2013·European Urology·Axel HeidenreichUNKNOWN European Association of Urology
Oct 3, 2014·Clinical Nuclear Medicine·Partha Sarathi ChakrabortyChandrasekhar Bal
Mar 21, 2015·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Matthias EiberMarkus Schwaiger
Sep 26, 2015·European Journal of Nuclear Medicine and Molecular Imaging·Florian SterzingFrederik L Giesel
Nov 3, 2016·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Wolfgang P FendlerClaudius Faber
Jun 13, 2016·European Journal of Nuclear Medicine and Molecular Imaging·Thomas PykaMatthias Eiber
Aug 26, 2016·European Journal of Nuclear Medicine and Molecular Imaging·Johannes SchwenckChristian la Fougère
Apr 18, 2018·Asia-Pacific Journal of Clinical Oncology·George HrubyAndrew Kneebone

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Citations

Apr 3, 2019·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Corey C FosterRalph R Weichselbaum
May 17, 2019·Nature Reviews. Clinical Oncology·Sean P Pitroda, Ralph R Weichselbaum
Dec 6, 2019·European Journal of Nuclear Medicine and Molecular Imaging·Daniela A FerraroIrene A Burger
Feb 16, 2019·Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]·Matthias Guckenberger

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