Comparative study of fractional Erbium: YAG laser vs combined therapy with topical steroid as an adjuvant treatment in melasma

Journal of Cosmetic Dermatology
Hamza Abdel-Raouf MohamedMira Abd El-Fatah Ahmed

Abstract

Melasma is an acquired disorder of symmetrical hyperpigmentation. Several treatment methods are available for patients with melasma, including topical compounds, broad-spectrum photoprotection, camouflage, chemical peels, and laser and light therapies which represent potentially promising options for patients who are refractory to other modalities. To evaluate and compare the clinical, histopathological, and immunohistochemical changes in melasma after fractional Er:YAG laser versus fractional Er:YAG laser and topical steroids. Twenty-two patients were treated with fractional Er:YAG laser on both sides of the face with the use of topical steroid only on the left side to make left-to-right-side comparison. Clinical evaluation, histopathological, and immunohistochemical assessment for skin specimens were performed before treatment and 3 months after the end of sessions. Treatment by fractional Er:YAG laser on the right side showed significant decrease in MASI score with clinical outcome which considered as excellent in three patients (13.6%), very good in six (27.2%), good in eight (36.3%), and fair in five (22.7%) with significant decrease in basal pigmentation and reorganization of dermal collagen and decreased number of MART1-...Continue Reading

References

Jan 1, 1994·Dermatology : International Journal for Clinical and Investigative Dermatology·A J KanwarS Kaur
Sep 27, 2003·The British Journal of Dermatology·R BalkrishnanM-M Chren
Jun 25, 2004·Lasers in Surgery and Medicine·Dieter MansteinR Rox Anderson
Jan 5, 2006·Lasers in Surgery and Medicine·Hans-Joachim LaubachDieter Manstein
Sep 13, 2006·Journal of Biomedical Optics·Basil M HantashKin Foong Chan
Nov 14, 2006·Journal of the American Academy of Dermatology·Aditya K GuptaSusan Taylor
Mar 17, 2007·The Journal of Dermatological Treatment·Manjiri D PawaskarRajesh Balkrishnan
Jan 15, 2008·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Emmy M GraberTina S Alster
Feb 29, 2008·Lasers in Surgery and Medicine·David J GoldbergRobert Phelps
Sep 30, 2009·Lasers in Medical Science·Inja Bogdan Allemann, Joely Kaufman
Oct 4, 2011·Indian Journal of Dermatology·Arun Achar, Sanjay K Rathi
Nov 19, 2011·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Kristel D Polder, Suzanne Bruce
Jan 4, 2012·Photodermatology, Photoimmunology & Photomedicine·Tag S AnbarAhmed Fawzy

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Citations

Jan 20, 2021·Dermatology and Therapy·Tamara SearleFiras Al-Niaimi
Apr 15, 2021·The Journal of Dermatological Treatment·Nicoleta NeaguCaterina Dianzani
May 19, 2020·The Journal of Dermatological Treatment·Sarah OtbAbeer Attia Tawfik

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