Comparative study of multiclass classification methods on light microscopic images for hepatic schistosomiasis fibrosis diagnosis

Health Information Science and Systems
Amira S AshourYanhui Guo

Abstract

Hepatic schistosomiasis is a prolonged disease resulting mainly from the solvable egg antigen of schistosomiasis infection due to the host's granulomatous cell-mediated immune. Irreversible fibrosis results from the progress of the schistosomal hepatopathy. Sensitive diagnosis of this disease is based on the investigation of the microscopy images, liver tissues, and egg identification. Early diagnosis of schistosomiasis at its initial infection stage is vital to avoid egg-induced irreparable pathological reactions. Typically, there are several classification approaches that can be used for liver fibrosis staging. However, it is unclear which approaches can achieve high accuracy for analyzing and intelligently classifying the liver microscopic images. Consequently, this work aims to study the performance of the different machine learning classifiers for accurate fibrosis level staging of granuloma, namely cellular, fibrocellular and fibrotic granulomas as well as the normal samples. The classifiers include a multi-layer perceptron neural network, a decision tree, discriminant analysis, support vector machine (SVM), nearest neighbor, and the ensemble of classifiers. The statistical features of the microscopic images are extracted...Continue Reading

References

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Citations

Jan 18, 2020·Health Information Science and Systems·Md ManiruzzamanMd Menhazul Abedin

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