Comparative study of right portal vein ligation versus embolisation for induction of hypertrophy in two-stage hepatectomy for multiple bilateral colorectal liver metastases

European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
R RoblesP Parrilla

Abstract

In patients with two-stage hepatectomy (TSH) for multiple bilobar liver metastases from colorectal cancer, few clinical series compare functional remnant hypertrophy of the liver volume between right portal vein ligation (PVL) and embolisation (PVE). Our objective is to analyse the effectiveness of portal vein ligation to achieve hypertrophy of the functional remnant volume (FRV) of the liver and to compare the results with portal vein embolisation in a series of patients with multiple bilobar liver metastases from colorectal carcinoma. Between September 2001 and September 2011 we performed a TSH in 41 patients with multiple bilobar colorectal liver metastases. A right PVL was performed in 23 patients with an insufficient FRV (three patients did not complete the second stage due to tumour progression and were excluded). We prospectively compare these results with the increased remnant volume obtained in 18 patients with right PVE. The median FRV was higher in the patients with PVE, rising from 501 ml (range 309-703) to 636 ml (range 387-649), than those with PVL, rising from 510 ml (range 203-824) to 595 ml (range 313-1213) (p < 0.05). The median %FRVI was higher in the patients with PVE (median 40%; range 21-65%) than those wi...Continue Reading

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Citations

Dec 7, 2013·Cardiovascular and Interventional Radiology·Dominik GeiselBernhard Gebauer
Feb 2, 2013·Journal of Vascular and Interventional Radiology : JVIR·Benjamin J MayDavid C Madoff
Dec 6, 2014·HPB Surgery : a World Journal of Hepatic, Pancreatic and Biliary Surgery·Santhalingam JegatheeswaranAjith K Siriwardena
Jun 8, 2015·Langenbeck's Archives of Surgery·Cui YangChristoph Reissfelder
Oct 8, 2013·Cirugía española·José Manuel RamiaJorge García-Parreño
Aug 6, 2014·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Yoshihiro MiseJean-Nicolas Vauthey
Mar 3, 2019·Journal of Surgical Oncology·Yoshikuni KawaguchiJean-Nicolas Vauthey
Nov 23, 2018·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Kristina HasselgrenBergthor Björnsson
Sep 1, 2018·Annals of Surgery·Per SandströmMagnus Rizell
Mar 30, 2017·Oncology Reports·Mahdi Hussain Al Bandar, Nam Kyu Kim
Mar 12, 2017·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Ernesto SparrelidBengt Isaksson
Jun 2, 2017·Langenbeck's Archives of Surgery·Nisha Narula, Thomas A Aloia
Apr 29, 2015·World Journal of Gastroenterology : WJG·Kristina HasselgrenBergthor Björnsson
Apr 1, 2016·Hepatic Oncology·Benjamin J May, David C Madoff
Oct 6, 2021·Journal of Surgical Oncology·Edoardo Maria MuttilloEmanuele Felli

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