Comparative study of the effects of several n-alkanes on phospholipid hexagonal phases

Biophysical Journal
Z Chen, R P Rand

Abstract

The effects of a series of normal alkanes (decane, dodecane, tetradecane, hexadecane, and octadecane) on the hexagonal H(II) structures containing dioleoylphosphatidylethanolamine (DOPE) and dioleoylphosphatidylcholine (DOPC) were studied using x-ray diffraction and osmotic stress. The alkanes affect structural dimensions and the monolayer intrinsic curvature and bending modulus. The alkane effects are chain-length dependent and are attributed to their different distribution within the H(II) structure. The data suggest that short-chain alkanes are more uniformly distributed within the H(II) hydrocarbon regions and change the curvature and bending modulus of the monolayer, whereas longer-chain alkanes appear confined more to the interstitial region and do not change the curvature and bending modulus.

References

Dec 20, 1979·Biochimica Et Biophysica Acta·P R Cullis, B de Kruijff
Jan 1, 1986·Faraday Discussions of the Chemical Society·S M GrunerR P Rand
Jun 1, 1985·Proceedings of the National Academy of Sciences of the United States of America·S M Gruner
Jul 19, 1996·Science·W R PerkinsA S Janoff
Jun 1, 1996·Biophysical Journal·M LafleurP R Cullis

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Citations

Oct 14, 2006·European Biophysics Journal : EBJ·Barry R Lentz
Jan 1, 2004·Journal of Biological Physics·Shu Jie Li, Masahito Yamazaki
Aug 29, 2003·Biophysical Journal·J A Szule, R P Rand
May 12, 2000·European Journal of Biochemistry·R M EpandD Schwarz
Oct 17, 2006·The European Physical Journal. E, Soft Matter·A HohnerJ O Rädler
Dec 27, 2012·The Journal of Chemical Physics·Alexander J Sodt, Richard W Pastor
Apr 2, 2014·Advances in Colloid and Interface Science·Isabelle MartielRaffaele Mezzenga
Jan 18, 2006·Chemistry and Physics of Lipids·Patricia UrbinaJesús Sot
May 28, 2013·Biophysical Journal·Alexander J Sodt, Richard W Pastor
May 19, 2010·Biochimica Et Biophysica Acta·Radka VladkovaBoris Tenchov
Jul 15, 2015·Biophysical Journal·Mariya ChavarhaStephen B Hall
Jun 5, 2015·European Biophysics Journal : EBJ·Christoph WollsteinSérgio S Funari
May 9, 2014·Biophysical Journal·Alexander J Sodt, Richard W Pastor
Aug 14, 2003·Biochimica Et Biophysica Acta·Joseph A Szule, Jens R Coorssen
Sep 23, 2008·Biophysical Journal·David P Siegel
Oct 8, 1999·Biophysical Journal·A ChanturiyaL V Chernomordik
Oct 19, 2006·Chemistry and Physics of Lipids·Derek Marsh
Nov 2, 2015·The Journal of Chemical Physics·Xin Wang, Markus Deserno
Apr 15, 2008·Chemistry and Physics of Lipids·Stephen H AlleyRichard H Templer
Jul 2, 2014·Soft Matter·Mária KlacsováPavol Balgavý
Jan 15, 1999·Acta Physiologica Scandinavica·J M ChalovichY D Chen
Jun 21, 2001·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·F RichterL Finegold
Nov 6, 2008·Molecular Membrane Biology·Xiaoyuan WangPeter J Quinn
Mar 29, 2014·Soft Matter·Benjamin KollmitzerGeorg Pabst
Dec 17, 2017·The Journal of Chemical Physics·I A Barragán Vidal, M Müller
Apr 19, 2019·Journal of Applied Crystallography·Moritz P K FreweinGeorg Pabst
Feb 12, 2021·The Journal of Physical Chemistry. B·Andrew H BeavenAlexander J Sodt
Jan 24, 2020·Biochimica Et Biophysica Acta. Biomembranes·Adrian Paz RamosMichel Lafleur
Feb 9, 2005·Biochemistry·Edgar E KooijmanPeter R Rand
Jul 16, 2021·Chemistry and Physics of Lipids·Marcus K Dymond
Aug 19, 2015·The Journal of Physical Chemistry Letters·Niklaus JohnerGeorge Khelashvili
Jan 31, 2018·Langmuir : the ACS Journal of Surfaces and Colloids·Ashish Jayaraman, Mahesh K Mahanthappa
Nov 16, 2018·Journal of Chemical Theory and Computation·Kevin J Boyd, Eric R May

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