PMID: 8612632Mar 1, 1996Paper

Comparative study of the sugar chains of alkaline phosphatases purified from rat liver and rat AH-130 hepatoma cells. Occurrence of fucosylated high-mannose-type and hybrid-type sugar chains

European Journal of Biochemistry
T EndoA Kobata

Abstract

The N-linked sugar chains of alkaline phosphatases, purified from rat AH-130 hepatoma and from normal rat liver, were released quantitatively as oligosaccharides by hydrazinolysis and were labeled by reduction with NaB3H4. A comparative study of their structures revealed that following structural differences are induced by hepatocyte carcinogenesis: complex-type tetraantennary sugar chains and hybrid-type sugar chains appear; outer-chain moieties of the sugar chains of the hepatoma enzyme contain exclusively the Gal(Beta 1-4)GlcNAc groups (type 2 chains) but those of the normal enzyme contain other Gal(Beta 1-)GlcNAc groups and type 2 chains; and novel fucosylated high-mannose-type sugar chains are found in the oligosaccharides of the hepatoma enzyme.

References

Jan 1, 1991·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·T EndoA Kobata
Oct 15, 1989·International Journal of Cancer. Journal International Du Cancer·S YagelJ W Dennis
Jan 1, 1989·Methods in Enzymology·A Kobata, K Yamashita
May 1, 1989·Journal of Biochemistry·M TakamotoA Kobata
Apr 1, 1986·Journal of Biochemistry·Y KozutsumiJ F Vliegenthart
Mar 1, 1985·Journal of Biochemistry·T TaniguchiA Kobata
Aug 1, 1972·Clinica Chimica Acta; International Journal of Clinical Chemistry·K HigashinoY Yamamura
Nov 1, 1974·American Journal of Clinical Pathology·D P Rhone, F M White
May 1, 1974·The American Journal of Medicine·W H Fishman
Sep 1, 1983·Canadian Journal of Biochemistry and Cell Biology = Revue Canadienne De Biochimie Et Biologie Cellulaire·H SchachterG Vella
Apr 1, 1984·Journal of Biochemistry·T MizuochiA Kobata
Jan 1, 1982·Methods in Enzymology·K YamashitaA Kobata
Jan 1, 1982·Methods in Enzymology·S TakasakiA Kobata
Oct 16, 1980·Biochemical and Biophysical Research Communications·K YamashitaA Kobata

❮ Previous
Next ❯

Citations

Mar 31, 2005·Biochemical and Biophysical Research Communications·Azin Nowrouzi, Razieh Yazdanparast
Dec 2, 1999·Biochimica Et Biophysica Acta·E StaudacherL März
Feb 19, 1999·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·X LiN E Huseby
Jun 7, 2017·Chemical Communications : Chem Comm·Danyang YinZhen Liu
Aug 15, 2019·Biological Reviews of the Cambridge Philosophical Society·Harry C TjondroMorten Thaysen-Andersen

❮ Previous
Next ❯

Related Concepts

Related Feeds

Adrenocortical Carcinoma

Hepatocellular carcinoma is the most common type of primary liver cancer and frequently occurs in individuals with chronic liver diseases like cirrhosis. Here is the latest research.

Carcinoma, Hepatocellular

Hepatocellular Carcinoma is a malignant cancer in liver epithelial cells. Discover the latest research on Hepatocellular Carcinoma here.