Comparative study of various models of experimental hydrocephalus.

Child's Brain
S MatsumotoK Fujiwara

Abstract

The authors present morphological findings in the brains of rabbits, dogs, cats, rats, and mice that have been used as experimental hydrocephalic models. The methods used were as follows: (1) silicone oil injection into the cisterna magna and the neighboring basal cisterns in rabbits by the method of Wisniewski; (2) kaolin administration into the cisterna magna in rabbits and dogs (Dixon); (3) ballooning method with Foley's catheter into the 4th ventricle in rabbits (Milho-rat); (4) plug formation with small pieces of laminalia into the cisterna magna in rabbits by our method; (5) Hy-3 hereditary hydrocephalic mouse bred by Gruenberg; (6) ligation of the placental vessels of the pregnant rat at 13 days of gestation by our method, and (7) transplacental intraperitoneal administration of ethylnitrosourea in a pregnant rat at 9.5 days of gestation. The models with silicone oil, kaolin, laminalia, and ballooning methods produced obstructive hydrocephalus with various grades of ventricular dilatation. The models with the ethylnitrosourea-induced method, ligation of placental vessels, and Hy-3 mouse produced prenatal hydrocephalus. Dilatation of the ventricular system and histological abnormalities do not occur as a uniform process.

Citations

Oct 16, 1999·Journal of Neuroscience Methods·M J JohnsonM G Luciano
May 24, 2003·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·N FukushimaT Moriizumi
Nov 1, 1985·Journal of Neurosurgery·J P McAllisterR C Truex
Sep 1, 1984·Surgical Neurology·J A BrownR L Wollmann
May 10, 2008·Journal of Neurosurgery·Michael A WilliamsGiovanna Spinella
Jul 1, 2020·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Jose L Peiro, Mateus Dal Fabbro

❮ Previous
Next ❯

Related Concepts

Related Feeds

Arrhythmogenic Right Ventricular Dysplasia

Arrhythmogenic right ventricular dysplasia is a congenital cardiomyopathy that is characterized by infiltration of adipose and fibrous tissue into the right ventricle wall and loss of myocardial cells. Primary injuries usually are at the free wall of the right ventricular and right atria resulting in ventricular and supraventricular arrhythmias. Discover the latest research on arrhythmogenic right ventricular dysplasia here.

© 2022 Meta ULC. All rights reserved