Comparative study on cytochrome P-450 of yeasts using specific antibodies to cytochromes P-450alk and P-450(14DM)

Yeast
E KaergelY Yoshida

Abstract

The occurrence of cytochrome P-450(14DM) (lanosterol 14 alpha-demethylase) and cytochrome P-450alk (long-chain alkane terminal hydroxylase) in various yeast strains was determined with immunological procedures. Cytochrome P-450(14DM), which is constitutive or housekeeping enzyme playing an essential role in ergosterol biogenesis, was found in all yeast strains so far tested. Cytochromes P-450(14DM) from different species of yeast were immunologically different, although they may have had a few common antigenic sites. In contrast, cytochrome P-450alk was detected only in the alkane-assimilating yeasts.

References

Nov 14, 1978·Biochemical and Biophysical Research Communications·Y Aoyama, Y Yoshida
May 14, 1986·Biochemical and Biophysical Research Communications·B WiedmannH G Müller
Jan 30, 1981·Biochemical and Biophysical Research Communications·P RiegeH G Müller

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