Comparative study on infection-induced thrombocytopenia among returned travellers.

Infection
K-H HerbingerG Bretzel

Abstract

Thrombocytopenia is a frequent finding among ill returned travellers and may be caused by a large number of different conditions, including infectious diseases specific or typical for tropical and subtropical regions. In order to assess the diagnostic significance of thrombocytopenia we investigated a large cohort of returned travellers. This was a comparative study in which data collected on 19,473 returned travellers who consulted the outpatient travel clinic of the the University of Munich Hospital between 1999 and 2009 were analysed. Of these, 732 (3.8%) travellers were diagnosed with thrombocytopenia, and their data were compared with those of the remaining 18,741 travellers with normal platelet counts. Thrombocytopenia was significantly more frequent among patients with malaria (63%), acute human immunodeficiency virus infection (48%), dengue fever/dengue haemorrhagic fever (DF/DHF; 47%), Epstein-Barr virus infectious mononucleosis (23%), paratyphoid/typhoid fever (14%), and rickettsiosis (12%). Malaria and DF/DHF caused 25% of all cases of thrombocytopenia (platelet count <140,000/μl) and 75% of all cases of severe thrombocytopenia (platelet count <30,000/μl). Sex, age, country of origin, duration and type of travel were...Continue Reading

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Citations

Mar 5, 2013·Infection·A S AntalT Herzinger
Dec 3, 2016·Journal of Medical Case Reports·Mohammed Al ReesiBrendan McMullan
Feb 24, 2016·The American Journal of Tropical Medicine and Hygiene·Karl-Heinz HerbingerMarcus Beissner
Oct 30, 2019·Therapeutic Apheresis and Dialysis : Official Peer-reviewed Journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy·Qiaoyan GuoPing Luo

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