PMID: 6375703Jun 1, 1984Paper

Comparative trial of iohexol 350, a non-ionic contrast medium, with diatrizoate (Urografin 370) in left ventriculography and coronary arteriography

British Heart Journal
I D SullivanE Sowton

Abstract

In a prospective double blind randomised study in 25 consecutive patients a conventional ionic contrast medium (Urografin 370) was compared with the new non-ionic medium iohexol 350 ( Omnipaque ) in left ventriculography and coronary arteriography. In left ventriculography there was a clear patient preference for iohexol by both a visual analogue scale and independent observer assessment. Iohexol also induced a smaller increase in heart rate or decrease in systolic blood pressure than Urografin. In coronary arteriography iohexol resulted in a smaller reduction in heart rate and systolic blood pressure, a smaller maximum increase in RR interval, less prolongation of the PQ and QT intervals and QRS duration, and a lower incidence of induced chest pain, ST segment depression, or T wave deflection.

References

Sep 1, 1978·Investigative Radiology·H W Fischer, K R Thomson
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Citations

Sep 1, 1990·The British Journal of Radiology·J F DyetW C Hartley
Nov 28, 2002·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·Enrique EsplugasFrancisco Jara
Oct 26, 1990·The American Journal of Cardiology·J A Brinker
Mar 1, 1991·Current Problems in Diagnostic Radiology·H O Stolberg, B L McClennan
Aug 27, 2005·Journal of the American Veterinary Medical Association·Fei SunManuel Maynar
Mar 1, 1989·In Vitro Cellular & Developmental Biology : Journal of the Tissue Culture Association·D Dichek, T Quertermous
Jul 1, 1985·Drug Intelligence & Clinical Pharmacy·T K Kawada
Jul 6, 2000·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·A BergstraH J Crijns

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