Comparative vasoactive effects of native and synthetic atrial natriuretic factor (ANF)

Biochemical and Biophysical Research Communications
R GarciaJ Genest

Abstract

The presence of a natriuretic factor in mammals atria has been confirmed by many laboratories. In addition to its natriuretic and diuretic activities, atrial preparation of uncertain degree of purification are known to contain a vasoactive substance. By the use of pure atrial natriuretic factor of known amino acid sequence and its synthetic homologue we have presented strong evidences suggesting that natriuretic and vasoactive activities are indeed mediated by the same peptide. As this peptide has not yet been detected in the circulation, its actual physiological relevance remains to be elucidated.

References

Jan 1, 1983·Clinical and Experimental Hypertension. Part A, Theory and Practice·J GenestP Hamet

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Citations

Dec 1, 1988·Cellular and Molecular Neurobiology·G Skofitsch, D M Jacobowitz
Jan 1, 1990·Pharmacology & Therapeutics·R J Winquist, T H Hintze
Oct 1, 1986·British Heart Journal·J Genest
Dec 1, 1985·The Journal of Clinical Investigation·B J Ballerman, B M Brenner
Apr 1, 1990·General and Comparative Endocrinology·K W ChiuP K Pang
Feb 13, 2001·Annual Review of Medicine·A Blum, H Miller
Jan 1, 1985·Clinical and Experimental Hypertension. Part A, Theory and Practice·R J WinquistE P Baskin
Jan 1, 1985·Clinical and Experimental Hypertension. Part A, Theory and Practice·R GarciaJ Genest
Jun 28, 1985·Biochemical and Biophysical Research Communications·T ObaraH Endou
Oct 15, 1991·Biochemical and Biophysical Research Communications·K N Pandey, M C Orgebin-Crist
Nov 27, 1986·The New England Journal of Medicine·T R SchwabJ C Burnett
Sep 1, 1988·British Journal of Clinical Pharmacology·D J WebbJ R Cockcroft
Mar 28, 1986·Biochemical and Biophysical Research Communications·R GarciaG Thibault
Mar 7, 1998·American Heart Journal·A Blum, H Miller

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