Compared with feeding infants breast milk or cow-milk formula, soy formula feeding does not affect subsequent reproductive organ size at 5 years of age

The Journal of Nutrition
Aline AndresThomas M Badger

Abstract

Literature reports suggest that phytochemicals, such as isoflavones found in soybeans, impair reproductive function in animals and raise the possibility that consuming soy infant formula could alter hormonally sensitive organ development in children. This study compared reproductive organs volumes and structural characteristics in children at age 5 y who were enrolled in the Beginnings study long-term cohort. Breast bud, uterus, ovaries, prostate, and testes volumes and characteristics were assessed by ultrasonography in 101 children (50 boys and 51 girls) aged 5 y who were breastfed (n = 35) or fed cow-milk formula (n = 32) or soy formula (n = 34) as infants. Analyses were adjusted for race, gestational age, and birth weight. Among girls, no significant differences were found in breast bud, ovarian, or uterine volumes; counts of ovaries with cysts; ovarian cysts numbers; ovarian cyst size; and uterine shape between the diet groups. Among boys, no significant differences were found in breast bud, testes, or prostate volumes or structural characteristics between the diet groups. In this cohort, no early infant feeding effects were found on reproductive organs volumes and structural characteristics in children age 5 y. The follow...Continue Reading

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References

Dec 1, 1979·The American Journal of Clinical Nutrition·S J FomonB B Edwards
Mar 1, 1996·The Proceedings of the Nutrition Society·A Cassidy
Dec 16, 1998·The American Journal of Clinical Nutrition·K D SetchellJ E Heubi
Dec 16, 1998·The American Journal of Clinical Nutrition·C H IrvineS L Alexander
Nov 2, 1999·Clinical Pediatrics·J B LasekanS Cho
Aug 22, 2001·JAMA : the Journal of the American Medical Association·B L StromS A Hanson
Mar 18, 2003·Nutrition Reviews·Ian C MunroHerman Adlercreutz
Apr 29, 2004·The Journal of Nutrition·Russell J Merritt, Belinda H Jenks
Jun 11, 2004·Annual Review of Nutrition·Aimin Chen, Walter J Rogan
Sep 21, 2004·Annual Review of Plant Biology·Richard A Dixon
Mar 13, 2008·Environmental Health Perspectives·Judy C BernbaumWalter J Rogan
May 3, 2008·Pediatrics·Jatinder BhatiaUNKNOWN American Academy of Pediatrics Committee on Nutrition
May 16, 2008·Environmental Research·Mary S WolffJoel Forman
Jul 31, 2008·Journal of Exposure Science & Environmental Epidemiology·Yang CaoWalter J Rogan
Jul 16, 2010·The American Journal of Clinical Nutrition·Guo ChengAnette E Buyken
Sep 29, 2011·Birth Defects Research. Part B, Developmental and Reproductive Toxicology·Gail McCarverKatie Turner
Jan 10, 2012·Reproduction : the Official Journal of the Society for the Study of Fertility·Wendy N JeffersonCarmen J Williams
Feb 14, 2012·Paediatric and Perinatal Epidemiology·Margaret A AdgentMichele Marcus
Jan 26, 2013·Epidemiology·Aimee A D'AloisioDale P Sandler

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Citations

Jan 21, 2016·Annual Review of Public Health·Eduardo Villamor, Erica C Jansen
May 18, 2016·International Journal of Environmental Research and Public Health·Wendy E WardElsa C Dinsdale
Jul 9, 2016·The Proceedings of the Nutrition Society·Heather B Patisaul
Mar 21, 2018·European Journal of Nutrition·Tali SinaiMarianna Rachmiel
Mar 6, 2018·The Journal of Clinical Endocrinology and Metabolism·Margaret A AdgentVirginia A Stallings
May 16, 2018·Experimental Biology and Medicine·Martin Jj RonisThomas M Badger
Jan 28, 2020·Pediatric Obesity·Melissa E Heard-LipsmeyerAline Andres
Apr 15, 2020·Paediatric and Perinatal Epidemiology·Helen B ChinDavid M Umbach
Dec 12, 2018·Frontiers in Nutrition·Ilaria TestaSusanna Esposito
Oct 11, 2017·Annual Review of Pharmacology and Toxicology·Martin J J RonisJames Watt
Jul 18, 2017·European Journal of Nutrition·Gina Segovia-SiapcoJoan Sabaté
Jul 17, 2016·Reproductive Toxicology·Shuk-Mei HoCarmen J Williams
May 19, 2021·PloS One·Flávia Ramos Kazan OliveiraVania Dos Santos Nunes-Nogueira

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