Comparing citrated native, kaolin-activated, and tissue factor-activated samples and determining intraindividual variability for feline thromboelastography

Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc
Amrita BanerjeeR Darren Wood

Abstract

Thromboelastography (TEG) is a point-of-care whole blood test of hemostasis. While TEG is becoming more widely used in veterinary medicine, few studies describe the use of TEG in cats. The objectives of the current study were to: 1) document the range of TEG variables produced in healthy cats using 3 sample types (citrated native, kaolin-activated, and tissue factor-activated), and 2) determine if there was a significant difference between 2 separate samples obtained from individual healthy cats on the same day. Jugular venipuncture was performed in 20 cats, and citrated blood collected for TEG. TEG analysis was performed on citrated native, kaolin-activated, and tissue factor-activated blood for each sample. Two hours later, the procedure was repeated from the opposite jugular vein, yielding a total of 120 analyses. Reaction time (R), alpha angle (α), kappa value (κ), and maximum amplitude (MA) were recorded from each tracing. No significant differences were found between TEG tracings from the first and second venipuncture samples. Significant differences were found between sample types for R, α, κ, and MA. Means for citrated native/kaolin-activated/tissue factor-activated methods were R = 4.1/3.7/0.6 min; κ = 2.5/1.8/2.2 min;...Continue Reading

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Citations

Mar 16, 2013·Blood Coagulation & Fibrinolysis : an International Journal in Haemostasis and Thrombosis·Sean L NeateNigel A Caulkett
Jan 30, 2014·Journal of Veterinary Emergency and Critical Care·Bente FlatlandBo Wiinberg
Jan 30, 2014·Journal of Veterinary Emergency and Critical Care·Rita M HanelBo Wiinberg
Jan 16, 2014·Journal of Veterinary Emergency and Critical Care·Armelle deLaforcadeBo Wiinberg
Oct 10, 2013·Veterinary Clinical Pathology·Sigrid Hyldahl LaursenBo Wiinberg
Jul 7, 2014·Journal of Dairy Science·Cora-Costanze SommereyJoy Archer
Jun 18, 2015·Journal of Veterinary Emergency and Critical Care·Bobbi J ConnerAdam J Birkenheuer
Apr 26, 2015·Research in Veterinary Science·E Döderlein, R Mischke
Sep 7, 2016·Journal of Veterinary Emergency and Critical Care·Hannah K JungeColin C Schwarzwald
Dec 22, 2016·Journal of Veterinary Emergency and Critical Care·Benoît CuqChristian Bédard
Jun 1, 2015·JFMS Open Reports·Shauna L BloisR Darren Wood
Apr 1, 2018·Journal of Veterinary Emergency and Critical Care·Robert GoggsCatherine Wagg
Sep 5, 2018·Journal of Feline Medicine and Surgery·Duree ShinKyoung Won Seo
Mar 13, 2019·Journal of Veterinary Internal Medicine·Junwoo BaeDohyeon Yu
Apr 25, 2018·American Journal of Veterinary Research·Beth A LieblickNathan W Peterson

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Methods Mentioned

BETA
blood draw

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