Comparing damage on retrieved total elbow replacement bushings with lab worn specimens subjected to varied loading conditions

Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society
Ryan Willing

Abstract

Complication rates following total elbow replacement (TER) with conventional implants are relatively high due to mechanical failure involving the UHMWPE bushings. Unfortunately, there are no standardized pre-clinical durability testing protocols for assessing the durability of TER components. This study examines the damage observed on retrieved humeral bushings, and then uses in vitro durability testing with two different loading protocols to compare resulting damage. Damage on 25 pairs of retrieved humeral bushings was characterized using micro-computed tomographic imaging techniques. The damage was compared with that of in vitro test specimens which were subjected to 200 K cycles of either high joint reaction force (high JRF) or high varus moment (high VM) loading. Material removal (mass loss) from bushing components was measured using gravimetric techniques. Thinning was less for retrieved bushings which were still assembled in their humeral component, versus bushings which were loose (0.3 ± 0.3 mm vs. 0.6 ± 0.3 mm, p = 0.02). Comparing in vitro test specimens, thinning due to high VM loading was 0.9 ± 0.3 mm, versus 0.2 ± 0.0 mm for high JRF loading (p = 0.08); however, the actual material removal rates from the humeral bus...Continue Reading

References

Dec 1, 2001·Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine·C Kaddick, M A Wimmer
Feb 22, 2005·Journal of Shoulder and Elbow Surgery·Thomas W Wright, Hill Hastings
May 4, 2005·The Journal of Bone and Joint Surgery. American Volume·Brian P LeeBernard F Morrey
Jul 20, 2007·Arthritis Research & Therapy·Yousef Abu-AmerJohn C Clohisy
Mar 4, 2008·The Journal of Bone and Joint Surgery. American Volume·Steven H GoldbergMark S Cohen
Jun 3, 2009·The Journal of Bone and Joint Surgery. American Volume·Andrea Celli, Bernard F Morrey
Mar 23, 2010·Journal of Shoulder and Elbow Surgery·William H SeitzPeter J Evans
Jun 3, 2010·The Journal of Bone and Joint Surgery. American Volume·Thomas ThrockmortonBernard Morrey
Feb 1, 2011·Journal of Shoulder and Elbow Surgery·Akin CilShawn W O'Driscoll
May 18, 2011·The Open Orthopaedics Journal·Joaquin Sanchez-Sotelo
Jul 10, 2012·Magnetic Resonance Imaging·Andriy FedorovRon Kikinis
Apr 16, 2013·Journal of Shoulder and Elbow Surgery·Judd S DayMarla J Steinbeck
Aug 28, 2013·Journal of Biomechanics·Brian L Kincaid, Kai-Nan An
May 2, 2015·Journal of Physical Therapy Science·Richard W Bohannon

❮ Previous
Next ❯

Citations

Jul 16, 2020·Journal of Shoulder and Elbow Surgery·Judd S DaySteven M Kurtz

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society
Ebru OralOrhun K Muratoglu
Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society
Sebastian FarrRudolf Ganger
Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society
Emily J MillerKenton R Kaufman
Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society
Zhen Lu, Edward Ebramzadeh
Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society
Zihui LiDavide Ruffoni
© 2022 Meta ULC. All rights reserved