Comparing diagnostic accuracy of Kato-Katz, Koga agar plate, ether-concentration, and FLOTAC for Schistosoma mansoni and soil-transmitted helminths.

PLoS Neglected Tropical Diseases
Dominik GlinzJürg Utzinger

Abstract

Infections with schistosomes and soil-transmitted helminths exert a considerable yet underappreciated economic and public health burden on afflicted populations. Accurate diagnosis is crucial for patient management, drug efficacy evaluations, and monitoring of large-scale community-based control programs. The diagnostic accuracy of four copromicroscopic techniques (i.e., Kato-Katz, Koga agar plate, ether-concentration, and FLOTAC) for the detection of Schistosoma mansoni and soil-transmitted helminth eggs was compared using stool samples from 112 school children in Côte d'Ivoire. Combined results of all four methods served as a diagnostic 'gold' standard and revealed prevalences of S. mansoni, hookworm, Trichuris trichiura, Strongyloides stercoralis and Ascaris lumbricoides of 83.0%, 55.4%, 40.2%, 33.9% and 28.6%, respectively. A single FLOTAC from stool samples preserved in sodium acetate-acetic acid-formalin for 30 or 83 days showed a higher sensitivity for S. mansoni diagnosis (91.4%) than the ether-concentration method on stool samples preserved for 40 days (85.0%) or triplicate Kato-Katz using fresh stool samples (77.4%). Moreover, a single FLOTAC detected hookworm, A. lumbricoides and T. trichiura infections with a higher...Continue Reading

References

Jan 1, 1988·Statistics in Medicine·J R LandisG G Koch
Sep 1, 1970·Journal of Clinical Pathology·A V Allen, D S Ridley
Dec 10, 1997·The American Journal of Tropical Medicine and Hygiene·D EngelsB Gryseels
Dec 3, 2003·Trends in Parasitology·Nilanthi R de SilvaLorenzo Savioli
Jul 17, 2004·International Journal of Epidemiology·Giovanna RasoJürg Utzinger
Aug 1, 1992·Parasitology Today·S J de Vlas, B Gryseels
Jun 21, 2006·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·I I BogochJ Utzinger
Sep 26, 2006·Lancet·Bruno GryseelsLuc Kestens
Sep 28, 2006·Nature Reviews. Microbiology·Rosanna W PeelingPatrick M M Bossuyt
Nov 18, 2006·Nature Reviews. Microbiology·Rosanna W PeelingPatrick M M Bossuyt
Oct 24, 2007·Annals of the New York Academy of Sciences·Peter Hotez
Nov 9, 2007·PLoS Neglected Tropical Diseases·Peter SteinmannJürg Utzinger
Nov 22, 2007·Transactions of the Royal Society of Tropical Medicine and Hygiene·Jürg UtzingerGiuseppe Cringoli
Nov 29, 2008·Transactions of the Royal Society of Tropical Medicine and Hygiene·Somphou SayasonePeter Odermatt
Jan 27, 2009·Transactions of the Royal Society of Tropical Medicine and Hygiene·Stefanie KnoppJürg Utzinger
Mar 10, 2009·Trends in Parasitology·Robert BergquistJürg Utzinger
Mar 31, 2009·Transactions of the Royal Society of Tropical Medicine and Hygiene·Annette OlsenPascal Magnussen
May 22, 2009·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·J UtzingerH Marti
Jul 4, 2009·Transactions of the Royal Society of Tropical Medicine and Hygiene·Stefanie KnoppJürg Utzinger
Jul 11, 2009·International Journal of Health Geographics·Simon BrookerRobert W Snow
Nov 18, 2009·The Journal of Parasitology·Dominik GlinzEliézer K N'Goran
Dec 8, 2009·Acta Tropica·Charles H King
Jul 16, 2010·Advances in Parasitology·Peter SteinmannXiao-Nong Zhou
Aug 20, 2010·Memórias do Instituto Oswaldo Cruz·Martin Johannes EnkVirginia Torres Schall

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Citations

Nov 26, 2013·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·B SpeichJ Keiser
May 3, 2011·PLoS Neglected Tropical Diseases·Stefanie KnoppJürg Utzinger
Jan 26, 2013·PLoS Neglected Tropical Diseases·Ana Requena-MéndezJosé Muñoz
Jan 10, 2014·Memórias do Instituto Oswaldo Cruz·Clélia Christina Mello-SilvaClaudia Portes Santos
Apr 21, 2012·Transactions of the Royal Society of Tropical Medicine and Hygiene·Jorge D MachicadoEduardo Gotuzzo
Apr 5, 2011·Current Infectious Disease Reports·Richard Bungiro, Michael Cappello
Nov 10, 2015·Current Tropical Medicine Reports·Poppy H L Lamberton, Peter M Jourdan
Aug 6, 2015·Parasitology Research·Takao IrieNariaki Nonaka
Aug 2, 2015·Pediatrics in Review·Jill E Weatherhead, Peter J Hotez
Apr 7, 2015·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·J UtzingerS Knopp
Apr 19, 2015·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·D BuonfrateZ Bisoffi
Apr 16, 2013·Veterinary Parasitology·Diana SindbergMaria Vang Johansen
May 16, 2013·PLoS Neglected Tropical Diseases·Alejandro J KrolewieckiMarco Albonico
Mar 4, 2014·PLoS Neglected Tropical Diseases·Anna M HoyAmy H Buck
Aug 15, 2014·PLoS Neglected Tropical Diseases·Santhosh PuthiyakunnonXiaoguang Chen
Jun 6, 2013·PLoS Neglected Tropical Diseases·Aïssatou DiawaraRoger K Prichard

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Methods Mentioned

BETA
scraping

Software Mentioned

FLOTAC
Office Access
STATA
EpiInfo

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