Comparing early signs and basic symptoms as methods for predicting psychotic relapse in clinical practice

Schizophrenia Research
Emily EisnerChristine Barrowclough

Abstract

Early signs interventions show promise but could be further developed. A recent review suggested that 'basic symptoms' should be added to conventional early signs to improve relapse prediction. This study builds on preliminary evidence that basic symptoms predict relapse and aimed to: 1. examine which phenomena participants report prior to relapse and how they describe them; 2. determine the best way of identifying pre-relapse basic symptoms; 3. assess current practice by comparing self- and casenote-reported pre-relapse experiences. Participants with non-affective psychosis were recruited from UK mental health services. In-depth interviews (n=23), verbal checklists of basic symptoms (n=23) and casenote extracts (n=208) were analysed using directed content analysis and non-parametric statistical tests. Three-quarters of interviewees reported basic symptoms and all reported conventional early signs and 'other' pre-relapse experiences. Interviewees provided rich descriptions of basic symptoms. Verbal checklist interviews asking specifically about basic symptoms identified these experiences more readily than open questions during in-depth interviews. Only 5% of casenotes recorded basic symptoms; interviewees were 16 times more lik...Continue Reading

Citations

Oct 5, 2018·Frontiers in Psychiatry·Frauke Schultze-LutterAnastasia Theodoridou
Jun 24, 2020·Fortschritte der Neurologie-Psychiatrie·Frauke Schultze-Lutter, Anastasia Theodoridou
Feb 10, 2021·Early Intervention in Psychiatry·Hadar HazanRichard J Linscott
Jan 15, 2021·International Journal of Environmental Research and Public Health·Omran DavarinejadSerge Brand

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