Comparing office-based and ambulatory blood pressure monitoring in clinical trials

Journal of Human Hypertension
W M VollmerDASH Collaborative Research Group

Abstract

Ambulatory blood pressure monitoring (ABPM) is commonly used in clinical trials. Yet, its ability to detect blood pressure (BP) change in comparison to multiple office-based measurements has received limited attention. We recorded ambulatory and five daily pairs of random zero (RZ) BPs pre- and post-intervention on 321 adult participants in the multicentre Dietary Approaches to Stop Hypertension trial. Treatment effect estimates measured by ambulatory monitoring were similar to those measured by RZ and did not differ significantly for waking vs 24-h ambulatory measurements. For systolic BP, the standard deviations of change in mean 24-h ambulatory BP (8.0 mmHg among hypertensives and 6.0 mmHg among nonhypertensives) were comparable to or lower than the corresponding standard deviations of change in RZ-BP based on five daily readings (8.9 and 5.9 mmHg). The standard deviations of change for mean waking ambulatory BP (8.7 and 6.7 mmHg) were comparable to those obtained using three to four daily RZ readings. Results for diastolic BP were qualitatively similar. Ambulatory monitoring was more efficient (ie, a smaller sample size could detect a given BP change) than three to four sets of daily RZ readings and required fewer clinic vi...Continue Reading

Associated Clinical Trials

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Citations

Jun 27, 2009·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Yasushi TanakaRyuzo Kawamori
Sep 17, 2010·The American Journal of Clinical Nutrition·Mustali M DohadwalaJoseph A Vita
Aug 15, 2013·American Journal of Health Promotion : AJHP·Jayan Marie Landry
Sep 18, 2010·Journal of Obesity·Nisa M MaruthurLawrence J Appel
Mar 21, 2013·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Michelle N EakinKristin A Riekert
Sep 1, 2015·American Journal of Preventive Medicine·Edgar R MillerHsin-Chieh Yeh
Apr 14, 2012·The Laryngoscope·Julina OngkasuwanMark S Courey
Jul 25, 2014·Evidence-based Complementary and Alternative Medicine : ECAM·Daniel M RicheMichael E Griswold
Nov 5, 2015·The Journal of Clinical Hypertension·Tammy M BradyEdgar R Miller
Apr 25, 2014·Expert Review of Pharmacoeconomics & Outcomes Research·Wen-Hung ChenSheri E Fehnel
Aug 17, 2019·Molecular Medicine·Marie HildermanAnnette Bruchfeld
Mar 17, 2020·Journal of Radiological Protection : Official Journal of the Society for Radiological Protection·K G VeinotK F Eckerman
Nov 26, 2015·Paediatric Drugs·Jason MisuracAmy C Wilson
Jul 28, 2019·American Journal of Hypertension·Stephen P JuraschekJennifer L Beach
Aug 8, 2018·The American Journal of Clinical Nutrition·Casey M Rebholz, Lawrence J Appel
Oct 9, 2020·Journal of Hypertension·Jamie J EdwardsJamie M O'Driscoll

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