Comparing patients' and their partners' preferences for adjuvant chemotherapy in early breast cancer

Patient Education and Counseling
V DuricM Stockler

Abstract

Preferences of women who had completed adjuvant chemotherapy for early breast cancer were compared with those of their partners by determining the smallest benefits they judged sufficient to make adjuvant chemotherapy worthwhile. Forty-six women and their partners were interviewed separately, 3-34 months after completing adjuvant chemotherapy. Preferences were elicited using four sets of validated, hypothetical trade-off scenarios about the possible benefits of adjuvant chemotherapy on survival times (5 and 15 years) and survival rates (65% and 85% at 5 years). Agreement within couples was assessed with the intraclass correlation coefficient (ICC). Associations between baseline characteristics, preferences, and agreement within couples were assessed with linear regression after normal score transformation. The mean age of the women was 57 years and of their partners' was 60. Most couples were married (91%). Benefits of an extra 1 day or 0.1% were judged sufficient to make adjuvant chemotherapy worthwhile by 59-72% of women and 54-59% of partners. Agreement was exact in 35-41% of couples and approximate in 59-83%. Agreement was better for scenarios with a worse prognosis (ICC 0.67 and 0.35) than for scenarios with a better progn...Continue Reading

References

Apr 1, 1992·Medical Decision Making : an International Journal of the Society for Medical Decision Making·H A Llewellyn-ThomasM J McGreal
Jun 1, 1994·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·G M KiebertH J de Haes
Feb 10, 1998·Medical Decision Making : an International Journal of the Society for Medical Decision Making·H J SutherlandJ E Till
Jul 23, 1998·Journal of Clinical Epidemiology·K C SneeuwJ H Schornagel
Aug 30, 2005·Annals of Oncology : Official Journal of the European Society for Medical Oncology·V M DuricR J Simes

❮ Previous
Next ❯

Citations

Dec 9, 2003·The Breast : Official Journal of the European Society of Mastology·H-J SennA S Coates
Dec 5, 2003·Annals of Surgical Oncology·Hiram S Cody
Nov 24, 2011·Breast Cancer : the Journal of the Japanese Breast Cancer Society·Naoki NiikuraYutaka Tokuda
Oct 22, 2011·Journal of Clinical Epidemiology·Manuela L FerreiraRob J Smeets
Sep 8, 2010·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·Prunella BlinmanMartin R Stockler
Feb 9, 2010·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Prunella BlinmanMartin Stockler
Oct 30, 2010·Health Expectations : an International Journal of Public Participation in Health Care and Health Policy·Sharon A CookPeter Salmon
Aug 11, 2011·Psycho-oncology·Justin M Yopp, Donald L Rosenstein
Apr 10, 2016·Breast Cancer Research and Treatment·Chalanda N EvansSuzanne C O'Neill
Jan 13, 2009·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Alison M BrownVal J Gebski
Oct 6, 2010·Clinical Breast Cancer·Marie E WoodHyman B Muss
Dec 26, 2009·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Weng NgMichael B Barton
Jul 1, 2010·Clinical Breast Cancer·Jennifer Eng-Wong, Claudine Isaacs
Jun 28, 2018·Oncology Nursing Forum·Victoria K Marshall, Barbara A Given

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Annals of Oncology : Official Journal of the European Society for Medical Oncology
V DuricR J Simes
European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)
R M BremnesE A Wist
Journal of the National Cancer Institute
S B YellenW T Leslie
The New England Journal of Medicine
B J McNeilS G Pauker
© 2022 Meta ULC. All rights reserved