Comparing pharmacologic mechanism of action for the vesicular monoamine transporter 2 (VMAT2) inhibitors valbenazine and deutetrabenazine in treating tardive dyskinesia: does one have advantages over the other?

CNS Spectrums
Stephen M Stahl

Abstract

The two approved treatments for tardive dyskinesia both inhibit the vesicular monoamine transporter type 2 (VMAT2) yet have pharmacologic properties that distinguish one from the other. Knowing these differences may help optimize which treatment to select for individual patients.

References

Dec 4, 2013·Journal of Medicinal Chemistry·Thomas G Gant
Mar 23, 2017·The American Journal of Psychiatry·Robert A HauserChristopher F O'Brien
Apr 14, 2017·The Journal of Pharmacology and Experimental Therapeutics·Dimitri E GrigoriadisHaig Bozigian
Apr 28, 2017·Neurology·Hubert H FernandezKaren E Anderson
Jul 26, 2017·Clinical Schizophrenia & Related Psychoses·Oliver Freudenreich, Gary Remington
Jan 18, 2018·Clinical Schizophrenia & Related Psychoses·Michael A CummingsStephen M Stahl
Feb 13, 2018·Journal of the Neurological Sciences·Laura M Scorr, Stewart A Factor

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Citations

Feb 1, 2019·Neurodegenerative Disease Management·Nicki Niemann, Joohi Jimenez-Shahed
Mar 15, 2019·Clinical Neuropharmacology·Nicki Niemann, Joseph Jankovic
May 2, 2019·Journal of Psychosocial Nursing and Mental Health Services·Barbara J Limandri
Nov 12, 2020·Expert Review of Neurotherapeutics·Benjamin J Dorfman, Joohi Jimenez-Shahed
May 27, 2020·Pharmacology & Therapeutics·Jessa KochKhashayar Dashtipour
Aug 10, 2021·Issues in Mental Health Nursing·Barbara WarrenJessica Johnson

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