Comparing pregnancy outcomes between natural cycles and artificial cycles following frozen-thaw embryo transfers.

The Australian & New Zealand Journal of Obstetrics & Gynaecology
Cassandra PakesAlex Polyakov

Abstract

Frozen embryo transfer (FET) is increasing in prevalence. In contrast to the amount of research performed on the actual cryopreservation procedure, there are limited data with respect to optimal endometrial preparation in FET cycles. Increasingly artificial cycle (AC) preparation is being adopted over the natural cycle (NC) to facilitate greater access to FET. However, there remains a paucity of data comparing pregnancy outcomes between these two commonly used cycle types. To examine the efficacy of AC vs NC following FET, by comparing pregnancy outcomes including biochemical, clinical and live birth rates, along with miscarriage rates. This is a large single-centre retrospective analysis, examining a standardised data set from January 2015 to July 2018. It included 3030 cycles (NC = 2033, AC = 997). Main outcomes were biochemical pregnancy (beta-human chorionic gonadotropin > 5 IU), ultrasound-diagnosed clinical pregnancy, and live births. Using the χ2 test, the above pregnancy outcomes were compared between AC and NC. A multivariate logistic regression, controlling for factors such as age, embryo quality, and day of blastocyst freeze was further utilised to assess for confounding variables. No difference was observed between ...Continue Reading

References

Aug 1, 1995·American Journal of Obstetrics and Gynecology·D F ArcherR G Foldesy
Nov 5, 1997·Annals of the New York Academy of Sciences·D De ZieglerA S Jääskeläinen
Jun 17, 2000·Fertility and Sterility·D K GardnerW B Schoolcraft
Apr 24, 2007·Journal of Assisted Reproduction and Genetics·Vadim MorozovSteven Brenner
Jan 5, 2011·Fertility and Sterility·Mark G Larman, David K Gardner
Mar 13, 2014·The Journal of Clinical Endocrinology and Metabolism·Richard J PaulsonVladimir I Yankov
Mar 29, 2014·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·Jacob LevronEldad Katorza
May 21, 2014·Fertility and Sterility·Bruce S ShapiroCynthia Hudson
Sep 12, 2015·Acta Obstetricia Et Gynecologica Scandinavica·Stefania Taraborrelli
Mar 15, 2016·Journal of Assisted Reproduction and Genetics·Raoul OrvietoJigal Haas
Mar 30, 2017·The Cochrane Database of Systematic Reviews·Kai Mee WongSebastiaan Mastenbroek
Apr 4, 2017·Fertility and Sterility·UNKNOWN Practice Committee of the American Society for Reproductive Medicine. Electronic address: ASRM@asrm.org, UNKNOWN Practice Committee of the American Society for Reproductive Medicine
Apr 25, 2017·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Quoc V LeMostafa I Abuzeid
May 4, 2017·Rambam Maimonides Medical Journal·Maria CerrilloJuan Antonio García-Velasco
Jan 16, 2019·Reproductive Biomedicine Online·Isabelle Cédrin-DurnerinMichael Grynberg
Mar 27, 2019·American Journal of Obstetrics and Gynecology·Erica Ginström ErnstadChristina Bergh

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