Comparing SARC-F with SARC-CalF for screening sarcopenia in advanced cancer patients.

Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition
Xiaofen FuShiying Yu

Abstract

Sarcopenia is a commonly prevalent malnutrition condition and serves as a valuable adverse prognostic indicator for survival in patients with cancer. A rapid and convenient screening test for sarcopenia would be helpful for patients. Aim of the study was to evaluate the diagnostic value of SARC-F and SARC-F combined with calf circumference (SARC-CalF) for screening cancer-related sarcopenia in cancer population. A total of 309 patients with cancer who had routine abdominal comptued tomography (CT) images within 30 days were enrolled in this cross-sectional cohort. Sarcopenia was determined as the presence of both low muscle mass (LMM) and low muscle strength; muscle mass was evaluated by CT-scan, and muscle strength was evaluated by handgrip strength (HGS). Two different diagnostic criteria (Western criteria and Eastern criteria) were used as the reference standards. The sensitivity and specificity analyses of the SARC-F and SARC-CalF were calculated. The receiver operating characteristic (ROC) curves and the area under the ROC curves (AUC) were used to compare the diagnostic value of SARC-F and SARC-CalF for sarcopenia. The prevalence of LMM and sarcopenia in the patient group was 85.1% and 50.5% by Western criteria. Correspon...Continue Reading

Citations

Aug 18, 2020·Nutrition & Dietetics : the Journal of the Dietitians Association of Australia·Nicole KissJudy Bauer
Dec 7, 2020·Experimental Gerontology·Marcella Campos Lima da LuzPoliana Coelho Cabral
Apr 4, 2021·Journal of Clinical Medicine·Anna Arnal-GómezNatalia Cezón-Serrano
May 15, 2021·European Journal of Clinical Nutrition·Cleidiana S BarretoGustavo D Pimentel

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