Comparing Short-term and Oncologic Outcomes of Minimally Invasive Versus Open Pancreaticoduodenectomy Across Low and High Volume Centers

Annals of Surgery
Robert J TorphyAna Gleisner

Abstract

To compare short-term and oncologic outcomes of patients with cancer who underwent open pancreaticoduodenectomy (OPD) versus minimally invasive pancreaticoduodenectomy (MIPD) using the National Cancer Database. MIPD, including laparoscopic and robotic approaches, has continued to gain acceptance despite prior reports of increased short-term mortality when compared with OPD. Patients with pancreatic cancer diagnosed from 2010 to 2015 undergoing curative intent resection were selected from the National Cancer Database. Patients submitted to OPD were compared with those submitted to MIPD. Laparoscopic and robotic approaches were included in the MIPD cohort. The primary outcome was 90-day mortality; secondary outcomes included 30-day mortality, hospital length of stay, unplanned 30-day readmission, surgical margins, number of lymph nodes harvested, and receipt of adjuvant chemotherapy. Propensity score-weighted random effects logistic regression models were used to examine the adjusted association between surgical approach and the specified outcomes. Between 2010 and 2015, 22,013 patients underwent OPD or MIPD for pancreatic cancer and 3754 (17.1%) were performed minimally invasively. On multivariable analysis, there was no differe...Continue Reading

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Citations

Mar 21, 2020·Scandinavian Journal of Surgery : SJS : Official Organ for the Finnish Surgical Society and the Scandinavian Surgical Society·L R JonesM G Besselink
Jun 23, 2020·Expert Review of Gastroenterology & Hepatology·Jiacheng WuXuewen Zhang
Jun 1, 2020·Surgery Today·Robert J TorphyRichard D Schulick
May 12, 2019·World Journal of Surgical Oncology·Mengqi LiuXiaowu Xu
Apr 22, 2020·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Richard S HoehnAmer H Zureikat
Aug 14, 2020·Langenbeck's Archives of Surgery·Ronggui LinHeguang Huang
Nov 22, 2018·Scandinavian Journal of Surgery : SJS : Official Organ for the Finnish Surgical Society and the Scandinavian Surgical Society·J-P LammiT Rantanen
Jul 17, 2020·Journal of Clinical Medicine·Daegwang YooSong Cheol Kim
Jun 23, 2019·Annals of Surgical Oncology·Robert J TorphyAna Gleisner
Nov 18, 2020·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·A Floortje van OostenJin He
Sep 20, 2019·Singapore Medical Journal·Tze-Yi LowBrian Kp Goh
Dec 29, 2020·Expert Review of Gastroenterology & Hepatology·Jiacheng WuYongsheng Yang
Jan 24, 2021·Updates in Surgery·Charles C ViningMelissa E Hogg
Oct 21, 2020·HPB : the Official Journal of the International Hepato Pancreato Biliary Association·Sivesh K KamarajahSteven A White
Feb 10, 2021·Journal of Surgical Oncology·Jason L Schwarz, Melissa E Hogg
Dec 15, 2019·HPB : the Official Journal of the International Hepato Pancreato Biliary Association·Alma L MoekotteUNKNOWN International Evidence-Based Guidelines on Minimally Invasive Pancreas Resection (IG-MIPR)
Nov 13, 2020·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·Michele MazzolaGiovanni Ferrari
Feb 4, 2021·Annals of Gastroenterological Surgery·Keinosuke IshidoTaiichi Wakiya
Mar 1, 2021·The British Journal of Surgery·S LofUNKNOWN European consortium on Minimally Invasive Pancreatic Surgery (E-MIPS)
Apr 4, 2021·International Journal of Molecular Sciences·Randa G Hanna-SawiresRob A E M Tollenaar
Apr 30, 2021·The Lancet. Gastroenterology & Hepatology·Min WangUNKNOWN Minimally Invasive Treatment Group in the Pancreatic Disease Branch of China's International Exchange and Promotion Associat
Jul 17, 2021·Annals of Surgical Oncology·Marcel Autran MachadoFabio Makdissi
Sep 23, 2020·Cirugía española·Francisco Espin AlvarezEsteban Cugat Andorrá

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